POTEE — 13 ClinVar variants
All ClinVar germline POTEE variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 1 flagged for review →
2 Benign · 11 Likely benign
Full POTEE gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 1
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All POTEE variants
Benign 2
- p.Glu378Asp Single submitter
- p.Gly99= Single submitter
Likely benign 11
- p.Ala719= Single submitter
- p.Ala82= Single submitter
- p.Ala930Thr Single submitter ⚠
- p.Arg728fs Single submitter
- p.Glu867Asp Single submitter
- p.Gly1001= Single submitter
- p.Gly973Asp Single submitter
- p.Leu157= Single submitter
- p.Leu191= Single submitter
- p.Leu804= Single submitter
- p.Val5Ile Single submitter