SCN2B — 244 ClinVar variants
All ClinVar germline SCN2B variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 113 flagged for review →
14 Conflicting · 13 Benign · 3 Benign/Likely benign · 92 Likely benign · 122 Uncertain significance
Full SCN2B gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 113
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 11
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
-
SCN2B p.Ala214Thr
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg28Gln
Conflicting
Single submitter
SCN2B-related disorder
-
SCN2B p.Arg28Trp
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg47His
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg84His
Conflicting
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg94Gln
Conflicting
Single submitter
Cardiovascular phenotype
-
SCN2B p.His2Arg
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Met113Thr
Conflicting
Single submitter
Cardiovascular phenotype
-
SCN2B p.Pro210Leu
Conflicting
Single submitter
Cardiovascular phenotype
-
SCN2B p.Thr193Arg
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Thr193Ile
Conflicting
Single submitter
atrial fibrillation, familial, 14
Predictors lean, ClinVar uncertain 68
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
-
SCN2B p.Ala171Pro
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Arg137His
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Arg154Gln
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Arg98Cys
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Arg98Gly
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Arg9His
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Asp211Gly
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Glu153Lys
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Gly138Ser
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Gly208Ser
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Leu14Phe
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Leu81Phe
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Met79Thr
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Pro49Ser
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Ser111Leu
Uncertain significance
Multiple submitters
dilated cardiomyopathy
-
SCN2B p.Ser18Asn
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Thr15Met
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Thr37Ile
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Val40Ile
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Ala11Thr
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ala164Ser
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ala46Thr
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg115Lys
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg185Lys
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg98His
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg9Cys
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asn116Asp
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asn126Asp
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asn131Ile
Uncertain significance
Single submitter
Cardiovascular phenotype
- SCN2B p.Asn209Thr Uncertain significance Single submitter
-
SCN2B p.Asn39Ser
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asn42Ser
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asn89Lys
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asp121Glu
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asp194Glu
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asp212His
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asp4Ala
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Asp4Val
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asp97Asn
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asp97Gly
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Glu188Gly
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Glu31Asp
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Gly123Arg
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Gly140Asp
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Gly163Asp
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Gly168Cys
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Gly206Ser
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.His2Pro
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Leu92Pro
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Leu92Val
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Lys186Arg
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Met130Leu
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
- SCN2B p.Met130Thr Uncertain significance Single submitter
-
SCN2B p.Met148Ile
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Phe12Val
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Phe52Leu
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Pro10Ser
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Pro132Thr
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Pro25Ala
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ser13Arg
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ser192Arg
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ser192Asn
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ser29Asn
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Thr198Ser
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Thr37Ala
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Val146Ile
Uncertain significance
Single submitter
Cardiovascular phenotype
- SCN2B p.Val162Gly Uncertain significance Single submitter
-
SCN2B p.Val183Met
Uncertain significance
Single submitter
Cardiovascular phenotype
Predictors split 34
The independent predictors disagree with each other — read with care.
-
SCN2B p.Arg135Cys
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Arg185Thr
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Arg84Cys
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Glu100Gly
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Glu149Gly
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Ile88Thr
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Met79Ile
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Pro151His
Uncertain significance
Multiple submitters
atrial fibrillation, familial, 14
-
SCN2B p.Tyr69His
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Val99Leu
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Val99Met
Uncertain significance
Multiple submitters
Cardiovascular phenotype
-
SCN2B p.Ala164Thr
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Ala171Thr
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg115Gly
Conflicting
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Arg137Cys
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg185Gly
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg185Ile
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg185Ser
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg84Leu
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Arg94Trp
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Asn126Lys
Likely benign
Single submitter
Cardiovascular phenotype
-
SCN2B p.Gly138Asp
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ile129Phe
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Met30Ile
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Met85Ile
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Phe101Leu
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Pro151Leu
Likely benign
Single submitter
Cardiovascular phenotype
-
SCN2B p.Pro151Thr
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Pro35Arg
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Pro35Ser
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Ser64Phe
Conflicting
Single submitter
Cardiovascular phenotype
-
SCN2B p.Thr157Lys
Uncertain significance
Single submitter
Cardiovascular phenotype
-
SCN2B p.Thr51Ile
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
-
SCN2B p.Val34Glu
Uncertain significance
Single submitter
atrial fibrillation, familial, 14
All SCN2B variants
Conflicting classifications of pathogenicity 14
- p.Ala214Thr Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg115Gly Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg28Gln Single submitter SCN2B-related disorder ⚠
- p.Arg28Trp Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg47His Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg84His Single submitter Cardiovascular phenotype ⚠
- p.Arg94Gln Single submitter Cardiovascular phenotype ⚠
- p.Asn209Pro Single submitter Cardiovascular phenotype
- p.His2Arg Single submitter atrial fibrillation, familial, 14 ⚠
- p.Met113Thr Single submitter Cardiovascular phenotype ⚠
- p.Pro210Leu Single submitter Cardiovascular phenotype ⚠
- p.Ser64Phe Single submitter Cardiovascular phenotype ⚠
- p.Thr193Arg Single submitter atrial fibrillation, familial, 14 ⚠
- p.Thr193Ile Single submitter atrial fibrillation, familial, 14 ⚠
Benign 13
- c.237+27A>G Multiple submitters
- c.237+76G>A Multiple submitters
- c.448+59G>A Multiple submitters
- c.449-12C>A Multiple submitters atrial fibrillation, familial, 14
- c.70+11_70+12insCT Multiple submitters atrial fibrillation, familial, 14
- c.*38C>T Multiple submitters
- c.448+103A>G Single submitter
- c.448+148C>T Single submitter
- c.449-130C>T Single submitter
- c.449-163C>G Single submitter
- c.449-167G>A Single submitter
- c.-488T>C Single submitter
- c.-511A>G Single submitter
Benign/Likely benign 3
- p.Gly43= Multiple submitters Cardiovascular phenotype
- p.Thr204= Multiple submitters Cardiovascular phenotype
- p.Val166Ile Multiple submitters atrial fibrillation, familial, 14
Likely benign 92
- c.449-78C>T Multiple submitters
- p.Ala159= Multiple submitters Cardiovascular phenotype
- p.Asn116= Multiple submitters atrial fibrillation, familial, 14
- p.Asn39= Multiple submitters Cardiovascular phenotype
- p.Asn42= Multiple submitters Cardiovascular phenotype
- p.Asn53= Multiple submitters Cardiovascular phenotype
- p.Asp109= Multiple submitters Cardiovascular phenotype
- p.Asp205= Multiple submitters Cardiovascular phenotype
- p.Asp45= Multiple submitters Cardiovascular phenotype
- p.Cys50= Multiple submitters atrial fibrillation, familial, 14
- p.Gln118= Multiple submitters Cardiovascular phenotype
- p.Gly123= Multiple submitters atrial fibrillation, familial, 14
- p.Gly213= Multiple submitters atrial fibrillation, familial, 14
- p.His136= Multiple submitters Cardiovascular phenotype
- p.Leu114= Multiple submitters atrial fibrillation, familial, 14
- p.Leu175= Multiple submitters atrial fibrillation, familial, 14
- p.Leu177= Multiple submitters Cardiovascular phenotype
- p.Leu48= Multiple submitters atrial fibrillation, familial, 14
- p.Lys107= Multiple submitters Cardiovascular phenotype
- p.Phe101= Multiple submitters Cardiovascular phenotype
- p.Pro119= Multiple submitters Cardiovascular phenotype
- p.Pro119Leu Multiple submitters Cardiovascular phenotype
- p.Pro132= Multiple submitters atrial fibrillation, familial, 14
- p.Ser13= Multiple submitters Cardiovascular phenotype
- p.Ser165= Multiple submitters Cardiovascular phenotype
- p.Thr157Met Multiple submitters Cardiovascular phenotype
- p.Thr198= Multiple submitters Cardiovascular phenotype
- p.Thr204Met Multiple submitters Cardiovascular phenotype
- p.Tyr108= Multiple submitters Cardiovascular phenotype
- p.Val32= Multiple submitters Cardiovascular phenotype
- c.237+11G>C Single submitter atrial fibrillation, familial, 14
- c.237+138T>C Single submitter
- c.237+19G>A Single submitter atrial fibrillation, familial, 14
- c.238-12C>A Single submitter atrial fibrillation, familial, 14
- c.238-18C>T Single submitter atrial fibrillation, familial, 14
- c.238-6C>T Single submitter atrial fibrillation, familial, 14
- c.448+13G>A Single submitter atrial fibrillation, familial, 14
- c.448+13G>T Single submitter atrial fibrillation, familial, 14
- c.449-13_449-12delinsAA Single submitter atrial fibrillation, familial, 14
- c.449-151G>T Single submitter
- c.449-15C>T Single submitter atrial fibrillation, familial, 14
- c.70+14A>G Single submitter atrial fibrillation, familial, 14
- c.70+14A>T Single submitter atrial fibrillation, familial, 14
- c.70+15T>C Single submitter atrial fibrillation, familial, 14
- c.70+17T>C Single submitter atrial fibrillation, familial, 14
- c.70+18G>C Single submitter atrial fibrillation, familial, 14
- c.71-13G>C Single submitter atrial fibrillation, familial, 14
- c.71-310G>A Single submitter
- c.-14_-12del Single submitter
- c.-24C>T Single submitter
- c.-34G>A Single submitter
- p.Ala36= Single submitter atrial fibrillation, familial, 14
- p.Arg135= Single submitter Cardiovascular phenotype
- p.Arg28= Single submitter Cardiovascular phenotype
- p.Arg47= Single submitter Cardiovascular phenotype
- p.Asn126Lys Single submitter Cardiovascular phenotype ⚠
- p.Asp195= Single submitter atrial fibrillation, familial, 14
- p.Cys182= Single submitter atrial fibrillation, familial, 14
- p.Cys55= Single submitter atrial fibrillation, familial, 14
- p.Gln145Arg Single submitter Cardiovascular phenotype
- p.Gln189= Single submitter atrial fibrillation, familial, 14
- p.Glu100= Single submitter atrial fibrillation, familial, 14
- p.Glu120= Single submitter Cardiovascular phenotype
- p.Glu153= Single submitter Cardiovascular phenotype
- p.Glu199= Single submitter Cardiovascular phenotype
- p.Glu200= Single submitter Cardiovascular phenotype
- p.Gly27= Single submitter atrial fibrillation, familial, 14
- p.His143Tyr Single submitter Cardiovascular phenotype
- p.Leu14= Single submitter Cardiovascular phenotype
- p.Leu17= Single submitter atrial fibrillation, familial, 14
- p.Leu170= Single submitter atrial fibrillation, familial, 14
- p.Leu196= Single submitter Cardiovascular phenotype
- p.Leu23= Single submitter atrial fibrillation, familial, 14
- p.Leu38= Single submitter atrial fibrillation, familial, 14
- p.Leu90= Single submitter atrial fibrillation, familial, 14
- p.Lys187= Single submitter atrial fibrillation, familial, 14
- p.Phe169= Single submitter Cardiovascular phenotype
- p.Phe52= Single submitter atrial fibrillation, familial, 14
- p.Pro133= Single submitter atrial fibrillation, familial, 14
- p.Pro151Leu Single submitter Cardiovascular phenotype ⚠
- p.Pro210= Single submitter atrial fibrillation, familial, 14
- p.Pro49Leu Single submitter Cardiovascular phenotype
- p.Ser111= Single submitter atrial fibrillation, familial, 14
- p.Ser156= Single submitter Cardiovascular phenotype
- p.Ser192= Single submitter Cardiovascular phenotype
- p.Thr15= Single submitter Cardiovascular phenotype
- p.Thr157= Single submitter atrial fibrillation, familial, 14
- p.Thr37= Single submitter atrial fibrillation, familial, 14
- p.Val160= Single submitter Cardiovascular phenotype
- p.Val166= Single submitter atrial fibrillation, familial, 14
- p.Val183= Single submitter Cardiovascular phenotype
- p.Val34= Single submitter
Uncertain significance 122
- p.Ala171Pro Multiple submitters Cardiovascular phenotype ⚠
- p.Arg135Cys Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Arg135His Multiple submitters SCN2B-related disorder
- p.Arg137His Multiple submitters Cardiovascular phenotype ⚠
- p.Arg154Gln Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Arg185Thr Multiple submitters Cardiovascular phenotype ⚠
- p.Arg84Cys Multiple submitters Cardiovascular phenotype ⚠
- p.Arg98Cys Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Arg98Gly Multiple submitters Cardiovascular phenotype ⚠
- p.Arg9His Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Asp109Asn Multiple submitters Cardiovascular phenotype
- p.Asp211Gly Multiple submitters Cardiovascular phenotype ⚠
- p.Glu100Gly Multiple submitters Cardiovascular phenotype ⚠
- p.Glu149Gly Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Glu153Lys Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Gly138Ser Multiple submitters Cardiovascular phenotype ⚠
- p.Gly208Ser Multiple submitters Cardiovascular phenotype ⚠
- p.Ile88Thr Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Leu14Phe Multiple submitters Cardiovascular phenotype ⚠
- p.Leu81Phe Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Lys215Met Multiple submitters atrial fibrillation, familial, 14
- p.Met79Ile Multiple submitters Cardiovascular phenotype ⚠
- p.Met79Thr Multiple submitters Cardiovascular phenotype ⚠
- p.Pro151His Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Pro49Ser Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Ser111Leu Multiple submitters dilated cardiomyopathy ⚠
- p.Ser18Asn Multiple submitters Cardiovascular phenotype ⚠
- p.Thr15Met Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Thr37Ile Multiple submitters atrial fibrillation, familial, 14 ⚠
- p.Tyr69His Multiple submitters Cardiovascular phenotype ⚠
- p.Val160Met Multiple submitters Cardiovascular phenotype
- p.Val40Ile Multiple submitters Cardiovascular phenotype ⚠
- p.Val99Leu Multiple submitters Cardiovascular phenotype ⚠
- p.Val99Met Multiple submitters Cardiovascular phenotype ⚠
- c.448+3G>A Single submitter atrial fibrillation, familial, 14
- c.448+6G>C Single submitter atrial fibrillation, familial, 14
- c.449-2A>C Single submitter atrial fibrillation, familial, 14
- c.71-1G>A Single submitter atrial fibrillation, familial, 14
- c.*5T>G Single submitter atrial fibrillation, familial, 14
- p.Ala11Thr Single submitter Cardiovascular phenotype ⚠
- p.Ala164Ser Single submitter Cardiovascular phenotype ⚠
- p.Ala164Thr Single submitter atrial fibrillation, familial, 14 ⚠
- p.Ala171Thr Single submitter Cardiovascular phenotype ⚠
- p.Ala46Thr Single submitter Cardiovascular phenotype ⚠
- p.Arg115Lys Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg137Cys Single submitter Cardiovascular phenotype ⚠
- p.Arg185Gly Single submitter Cardiovascular phenotype ⚠
- p.Arg185Ile Single submitter Cardiovascular phenotype ⚠
- p.Arg185Lys Single submitter atrial fibrillation, familial, 14 ⚠
- p.Arg185Ser Single submitter Cardiovascular phenotype ⚠
- p.Arg47Cys Single submitter atrial fibrillation, familial, 14
- p.Arg84Leu Single submitter Cardiovascular phenotype ⚠
- p.Arg94Trp Single submitter Cardiovascular phenotype ⚠
- p.Arg98His Single submitter Cardiovascular phenotype ⚠
- p.Arg9Cys Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asn116Asp Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asn126Asp Single submitter Cardiovascular phenotype ⚠
- p.Asn131Ile Single submitter Cardiovascular phenotype ⚠
- p.Asn209Thr Single submitter ⚠
- p.Asn39Ser Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asn42Ser Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asn89Lys Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asp121Glu Single submitter Cardiovascular phenotype ⚠
- p.Asp194Glu Single submitter Cardiovascular phenotype ⚠
- p.Asp212His Single submitter Cardiovascular phenotype ⚠
- p.Asp4Ala Single submitter atrial fibrillation, familial, 14 ⚠
- p.Asp4Val Single submitter Cardiovascular phenotype ⚠
- p.Asp97Asn Single submitter Cardiovascular phenotype ⚠
- p.Asp97Gly Single submitter atrial fibrillation, familial, 14 ⚠
- p.Glu188Gly Single submitter atrial fibrillation, familial, 14 ⚠
- p.Glu200Lys Single submitter Cardiovascular phenotype
- p.Glu201Val Single submitter atrial fibrillation, familial, 14
- p.Glu31Asp Single submitter atrial fibrillation, familial, 14 ⚠
- p.Gly123Arg Single submitter atrial fibrillation, familial, 14 ⚠
- p.Gly138Asp Single submitter Cardiovascular phenotype ⚠
- p.Gly140= Single submitter atrial fibrillation, familial, 14
- p.Gly140Asp Single submitter atrial fibrillation, familial, 14 ⚠
- p.Gly163Asp Single submitter Cardiovascular phenotype ⚠
- p.Gly168Cys Single submitter atrial fibrillation, familial, 14 ⚠
- p.Gly206Ser Single submitter atrial fibrillation, familial, 14 ⚠
- p.His2Pro Single submitter Cardiovascular phenotype ⚠
- p.Ile129Phe Single submitter Cardiovascular phenotype ⚠
- p.Ile174Leu Single submitter Cardiovascular phenotype
- p.Ile174Met Single submitter atrial fibrillation, familial, 14
- p.Leu114_Gln118del Single submitter atrial fibrillation, familial, 14
- p.Leu41Pro Single submitter atrial fibrillation, familial, 14
- p.Leu92Pro Single submitter Cardiovascular phenotype ⚠
- p.Leu92Val Single submitter atrial fibrillation, familial, 14 ⚠
- p.Lys186Arg Single submitter atrial fibrillation, familial, 14 ⚠
- p.Lys186Glu Single submitter atrial fibrillation, familial, 14
- p.Met130Leu Single submitter atrial fibrillation, familial, 14 ⚠
- p.Met130Thr Single submitter ⚠
- p.Met148Ile Single submitter Cardiovascular phenotype ⚠
- p.Met30Ile Single submitter atrial fibrillation, familial, 14 ⚠
- p.Met85Ile Single submitter atrial fibrillation, familial, 14 ⚠
- p.Phe101Leu Single submitter Cardiovascular phenotype ⚠
- p.Phe12Val Single submitter Cardiovascular phenotype ⚠
- p.Phe52Leu Single submitter atrial fibrillation, familial, 14 ⚠
- p.Pro10Ser Single submitter atrial fibrillation, familial, 14 ⚠
- p.Pro132Thr Single submitter Cardiovascular phenotype ⚠
- p.Pro133_Asp134insTer Single submitter
- p.Pro151Thr Single submitter atrial fibrillation, familial, 14 ⚠
- p.Pro25Ala Single submitter Cardiovascular phenotype ⚠
- p.Pro25fs Single submitter Cardiovascular phenotype
- p.Pro35Arg Single submitter Cardiovascular phenotype ⚠
- p.Pro35Ser Single submitter Cardiovascular phenotype ⚠
- p.Ser13Arg Single submitter Cardiovascular phenotype ⚠
- p.Ser192Arg Single submitter Cardiovascular phenotype ⚠
- p.Ser192Asn Single submitter Cardiovascular phenotype ⚠
- p.Ser192fs Single submitter atrial fibrillation, familial, 14
- p.Ser29Asn Single submitter atrial fibrillation, familial, 14 ⚠
- p.Thr157Lys Single submitter Cardiovascular phenotype ⚠
- p.Thr198Ser Single submitter Cardiovascular phenotype ⚠
- p.Thr37Ala Single submitter atrial fibrillation, familial, 14 ⚠
- p.Thr51Ile Single submitter atrial fibrillation, familial, 14 ⚠
- p.Val117Met Single submitter atrial fibrillation, familial, 14
- p.Val146Ile Single submitter Cardiovascular phenotype ⚠
- p.Val162Gly Single submitter ⚠
- p.Val180Gly Single submitter Cardiovascular phenotype
- p.Val183Met Single submitter Cardiovascular phenotype ⚠
- p.Val34Glu Single submitter atrial fibrillation, familial, 14 ⚠
- p.Val58Met Single submitter Cardiovascular phenotype