SLC29A2 — 62 ClinVar variants
All ClinVar germline SLC29A2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 54 flagged for review →
3 Likely benign · 59 Uncertain significance
Full SLC29A2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 54
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 44
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- SLC29A2 p.Ala132Ser Uncertain significance Single submitter
- SLC29A2 p.Ala132Val Uncertain significance Single submitter
- SLC29A2 p.Ala230Val Uncertain significance Single submitter
- SLC29A2 p.Ala310Thr Uncertain significance Single submitter
- SLC29A2 p.Ala41Val Uncertain significance Single submitter
- SLC29A2 p.Ala446Asp Uncertain significance Single submitter
- SLC29A2 p.Arg359Gln Uncertain significance Single submitter
- SLC29A2 p.Arg359Trp Uncertain significance Single submitter
- SLC29A2 p.Arg383Lys Uncertain significance Single submitter
- SLC29A2 p.Arg383Thr Uncertain significance Single submitter
- SLC29A2 p.Arg98His Uncertain significance Single submitter
- SLC29A2 p.Asn247Lys Uncertain significance Single submitter
- SLC29A2 p.Asn247Thr Uncertain significance Single submitter
- SLC29A2 p.Asp357His Uncertain significance Single submitter
- SLC29A2 p.Gln229Arg Uncertain significance Single submitter
- SLC29A2 p.Gln392Arg Uncertain significance Single submitter
- SLC29A2 p.Glu189Lys Uncertain significance Single submitter
- SLC29A2 p.Glu240Asp Uncertain significance Single submitter
- SLC29A2 p.Glu267Ala Uncertain significance Single submitter
- SLC29A2 p.Gly124Ala Uncertain significance Single submitter
- SLC29A2 p.Gly166Ser Uncertain significance Single submitter
- SLC29A2 p.Gly185Asp Uncertain significance Single submitter
- SLC29A2 p.Gly22Arg Uncertain significance Single submitter
- SLC29A2 p.Gly408Ala Uncertain significance Single submitter
- SLC29A2 p.Gly45Arg Uncertain significance Single submitter
- SLC29A2 p.His58Asp Uncertain significance Single submitter
- SLC29A2 p.Ile249Val Uncertain significance Single submitter
- SLC29A2 p.Ile99Val Uncertain significance Single submitter
- SLC29A2 p.Leu162His Uncertain significance Single submitter
- SLC29A2 p.Leu27Phe Uncertain significance Single submitter
- SLC29A2 p.Leu73Arg Uncertain significance Single submitter
- SLC29A2 p.Met131Lys Uncertain significance Single submitter
- SLC29A2 p.Pro278Ala Uncertain significance Single submitter
- SLC29A2 p.Ser139Phe Uncertain significance Single submitter
- SLC29A2 p.Ser139Tyr Uncertain significance Single submitter
- SLC29A2 p.Ser160Thr Uncertain significance Single submitter
- SLC29A2 p.Ser252Asn Uncertain significance Single submitter
- SLC29A2 p.Thr190Ser Uncertain significance Single submitter
- SLC29A2 p.Thr414Ser Uncertain significance Single submitter
- SLC29A2 p.Thr59Arg Uncertain significance Single submitter
- SLC29A2 p.Tyr221His Uncertain significance Single submitter
- SLC29A2 p.Val201Met Uncertain significance Single submitter
- SLC29A2 p.Val307Ile Uncertain significance Single submitter
- SLC29A2 p.Val429Met Uncertain significance Single submitter
Predictors split 10
The independent predictors disagree with each other — read with care.
- SLC29A2 p.Gly431Ser Uncertain significance Single submitter
- SLC29A2 p.Leu148Phe Uncertain significance Single submitter
- SLC29A2 p.Met131Val Uncertain significance Single submitter
- SLC29A2 p.Met155Val Uncertain significance Single submitter
- SLC29A2 p.Met178Thr Uncertain significance Single submitter
- SLC29A2 p.Met400Val Uncertain significance Single submitter
- SLC29A2 p.Met415Thr Uncertain significance Single submitter
- SLC29A2 p.Thr348Asn Uncertain significance Single submitter
- SLC29A2 p.Thr59Met Uncertain significance Single submitter
- SLC29A2 p.Val380Met Uncertain significance Single submitter
All SLC29A2 variants
Likely benign 3
- p.Ala115Val Single submitter
- p.Cys92= Single submitter
- p.Gly47Ser Single submitter
Uncertain significance 59
- p.Ala132Ser Single submitter ⚠
- p.Ala132Val Single submitter ⚠
- p.Ala230Val Single submitter ⚠
- p.Ala310Thr Single submitter ⚠
- p.Ala41Val Single submitter ⚠
- p.Ala446Asp Single submitter ⚠
- p.Arg359Gln Single submitter ⚠
- p.Arg359Trp Single submitter ⚠
- p.Arg383Lys Single submitter ⚠
- p.Arg383Thr Single submitter ⚠
- p.Arg98His Single submitter ⚠
- p.Asn247Lys Single submitter ⚠
- p.Asn247Thr Single submitter ⚠
- p.Asp357His Single submitter ⚠
- p.Gln229Arg Single submitter ⚠
- p.Gln392Arg Single submitter ⚠
- p.Glu189Lys Single submitter ⚠
- p.Glu240Asp Single submitter ⚠
- p.Glu267Ala Single submitter ⚠
- p.Glu426Lys Single submitter
- p.Gly124Ala Single submitter ⚠
- p.Gly166Ser Single submitter ⚠
- p.Gly185Asp Single submitter ⚠
- p.Gly22Arg Single submitter ⚠
- p.Gly408Ala Single submitter ⚠
- p.Gly431Ser Single submitter ⚠
- p.Gly45Arg Single submitter ⚠
- p.His58Asp Single submitter ⚠
- p.Ile249Val Single submitter ⚠
- p.Ile99Val Single submitter ⚠
- p.Leu148Phe Single submitter ⚠
- p.Leu162His Single submitter ⚠
- p.Leu180Arg Single submitter
- p.Leu27Phe Single submitter ⚠
- p.Leu451His Single submitter
- p.Leu73Arg Single submitter ⚠
- p.Met131Lys Single submitter ⚠
- p.Met131Val Single submitter ⚠
- p.Met155Val Single submitter ⚠
- p.Met178Thr Single submitter ⚠
- p.Met400Val Single submitter ⚠
- p.Met415Thr Single submitter ⚠
- p.Phe88Ser Single submitter
- p.Pro278Ala Single submitter ⚠
- p.Ser139Phe Single submitter ⚠
- p.Ser139Tyr Single submitter ⚠
- p.Ser160Thr Single submitter ⚠
- p.Ser252Asn Single submitter ⚠
- p.Thr190Ser Single submitter ⚠
- p.Thr348Asn Single submitter ⚠
- p.Thr414Ser Single submitter ⚠
- p.Thr59Arg Single submitter ⚠
- p.Thr59Met Single submitter ⚠
- p.Tyr221His Single submitter ⚠
- p.Val134Phe Single submitter
- p.Val201Met Single submitter ⚠
- p.Val307Ile Single submitter ⚠
- p.Val380Met Single submitter ⚠
- p.Val429Met Single submitter ⚠