STMN2 — 7 ClinVar variants
All ClinVar germline STMN2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 3 flagged for review →
7 Uncertain significance
Full STMN2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 3
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 2
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All STMN2 variants
Uncertain significance 7
- c.481-1168A>G Single submitter
- c.481-1193T>C Single submitter
- c.481-1208A>G Single submitter
- p.Arg114Gln Single submitter ⚠
- p.Glu82Lys Single submitter
- p.Glu89Asp Single submitter ⚠
- p.Ile34Thr Single submitter ⚠