TCF7 — 66 ClinVar variants
All ClinVar germline TCF7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.
3 Likely benign · 63 Uncertain significance
Full TCF7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactionsAll TCF7 variants
Likely benign 3
- p.Asn167Ser Single submitter
- p.Pro134= Single submitter
- p.Ser123= Single submitter
Uncertain significance 63
- p.Ala109Ser Single submitter
- p.Ala150Thr Single submitter
- p.Ala364Thr Single submitter
- p.Ala373Thr Single submitter
- p.Ala41Thr Single submitter
- p.Ala42Val Single submitter
- p.Ala74Thr Single submitter
- p.Ala78Thr Single submitter
- p.Arg250Ser Single submitter
- p.Arg348Trp Single submitter
- p.Arg362Gly Single submitter
- p.Arg46Cys Single submitter
- p.Asp105Gly Single submitter
- p.Asp28Asn Single submitter
- p.Asp47Ala Single submitter
- p.Asp5Gly Single submitter
- p.Cys112Tyr Single submitter
- p.Gln92Glu Single submitter
- p.Glu111Ala Single submitter
- p.Glu111Gln Single submitter
- p.Glu83Lys Single submitter
- p.Gly13Arg Single submitter
- p.Gly156Ser Single submitter
- p.Gly343Arg Single submitter
- p.Gly65Ser Single submitter
- p.Gly73Arg Single submitter
- p.Gly75Cys Single submitter
- p.Gly77Arg Single submitter
- p.Gly8Arg Single submitter
- p.His140Arg Single submitter
- p.His140Asp Single submitter
- p.His170Arg Single submitter
- p.His353Tyr Single submitter
- p.Ile236Phe Single submitter
- p.Ile288Thr Single submitter
- p.Leu160Pro Single submitter
- p.Phe95Leu Single submitter
- p.Pro100Gln Single submitter
- p.Pro100Leu Single submitter
- p.Pro134Arg Single submitter
- p.Pro134His Single submitter
- p.Pro153Arg Single submitter
- p.Pro153His Single submitter
- p.Pro154Arg Single submitter
- p.Pro169Ala Single submitter
- p.Pro186Arg Single submitter
- p.Pro190Leu Single submitter
- p.Pro20Ser Single submitter
- p.Pro228Arg Single submitter
- p.Pro239His Single submitter
- p.Pro375Arg Single submitter
- p.Pro377Leu Single submitter
- p.Pro72Leu Single submitter
- p.Ser161Thr Single submitter
- p.Ser258Phe Single submitter
- p.Ser40Thr Single submitter
- p.Thr120Ile Single submitter
- p.Thr357Ala Single submitter
- p.Thr358Lys Single submitter
- p.Tyr319Cys Single submitter
- p.Val121Ile Single submitter
- p.Val287Leu Single submitter
- p.Val71Gly Single submitter