Sugi Variant

Sugi Variant/TET2

TET2 — 2007 ClinVar variants

All ClinVar germline TET2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 1119 flagged for review →

149 Pathogenic · 2 Pathogenic/Likely pathogenic · 22 Likely pathogenic · 11 Conflicting · 26 Benign · 12 Benign/Likely benign · 573 Likely benign · 1212 Uncertain significance

Full TET2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 1119

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 5

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 1057

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 1057

Predictors split 57

The independent predictors disagree with each other — read with care.

All TET2 variants

Pathogenic 149

Pathogenic/Likely pathogenic 2

Likely pathogenic 22

Conflicting classifications of pathogenicity 11

Benign 26

Benign/Likely benign 12

Likely benign 573

Showing the top 300 by review status; the full set is in the sitemap.

Uncertain significance 1212

Showing the top 300 by review status; the full set is in the sitemap.