TEX13A — 39 ClinVar variants
All ClinVar germline TEX13A variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 32 flagged for review →
7 Likely benign · 32 Uncertain significance
Full TEX13A gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 32
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 31
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- TEX13A p.Ala165Ser Uncertain significance Single submitter
- TEX13A p.Ala173Thr Uncertain significance Single submitter
- TEX13A p.Ala193Glu Uncertain significance Single submitter
- TEX13A p.Ala387Val Uncertain significance Single submitter
- TEX13A p.Ala83Thr Uncertain significance Single submitter
- TEX13A p.Arg143Lys Uncertain significance Single submitter
- TEX13A p.Arg361Gly Uncertain significance Single submitter
- TEX13A p.Arg370Gly Uncertain significance Single submitter
- TEX13A p.Arg77His Uncertain significance Single submitter
- TEX13A p.Arg89Gly Uncertain significance Single submitter
- TEX13A p.Cys169Tyr Uncertain significance Single submitter
- TEX13A p.Glu116Gln Uncertain significance Single submitter
- TEX13A p.Glu119Gly Uncertain significance Single submitter
- TEX13A p.Glu121Gln Uncertain significance Single submitter
- TEX13A p.Glu124Lys Uncertain significance Single submitter
- TEX13A p.Glu37Gly Uncertain significance Single submitter
- TEX13A p.Glu44Lys Uncertain significance Single submitter
- TEX13A p.Glu58Lys Uncertain significance Single submitter
- TEX13A p.Gly161Asp Uncertain significance Single submitter
- TEX13A p.Gly166Arg Uncertain significance Single submitter
- TEX13A p.His88Asn Uncertain significance Single submitter
- TEX13A p.Lys113Gln Uncertain significance Single submitter
- TEX13A p.Lys98Asn Uncertain significance Single submitter
- TEX13A p.Met131Ile Uncertain significance Single submitter
- TEX13A p.Phe12Cys Uncertain significance Single submitter
- TEX13A p.Phe390Ser Uncertain significance Single submitter
- TEX13A p.Pro330Ser Uncertain significance Single submitter
- TEX13A p.Pro5Arg Uncertain significance Single submitter
- TEX13A p.Pro8Thr Uncertain significance Single submitter
- TEX13A p.Ser288Leu Uncertain significance Single submitter
- TEX13A p.Thr29Met Uncertain significance Single submitter
Predictors split 1
The independent predictors disagree with each other — read with care.
All TEX13A variants
Likely benign 7
- p.Ala132Thr Single submitter
- p.Arg13Gln Single submitter
- p.His350Gln Single submitter
- p.Ile53= Single submitter
- p.Ser312Pro Single submitter
- p.Ser345= Single submitter
- p.Val270= Single submitter
Uncertain significance 32
- p.Ala165Ser Single submitter ⚠
- p.Ala173Thr Single submitter ⚠
- p.Ala193Glu Single submitter ⚠
- p.Ala387Val Single submitter ⚠
- p.Ala83Thr Single submitter ⚠
- p.Arg143Lys Single submitter ⚠
- p.Arg361Gly Single submitter ⚠
- p.Arg370Gly Single submitter ⚠
- p.Arg77His Single submitter ⚠
- p.Arg89Gly Single submitter ⚠
- p.Cys169Tyr Single submitter ⚠
- p.Glu116Gln Single submitter ⚠
- p.Glu119Gly Single submitter ⚠
- p.Glu121Gln Single submitter ⚠
- p.Glu124Lys Single submitter ⚠
- p.Glu37Gly Single submitter ⚠
- p.Glu44Lys Single submitter ⚠
- p.Glu58Lys Single submitter ⚠
- p.Gly161Asp Single submitter ⚠
- p.Gly166Arg Single submitter ⚠
- p.His88Asn Single submitter ⚠
- p.Lys113Gln Single submitter ⚠
- p.Lys98Asn Single submitter ⚠
- p.Met131Ile Single submitter ⚠
- p.Phe12Cys Single submitter ⚠
- p.Phe390Ser Single submitter ⚠
- p.Pro330Ser Single submitter ⚠
- p.Pro5Arg Single submitter ⚠
- p.Pro8Thr Single submitter ⚠
- p.Ser10Arg Single submitter ⚠
- p.Ser288Leu Single submitter ⚠
- p.Thr29Met Single submitter ⚠