TLR3 — 589 ClinVar variants

All ClinVar germline TLR3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 342 flagged for review →

7 Conflicting · 11 Benign · 10 Benign/Likely benign · 163 Likely benign · 398 Uncertain significance

Full TLR3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 342

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 5

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

TLR3 p.Arg394Gln Conflicting Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu663Lys Conflicting Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His319Gln Conflicting Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu297Val Conflicting Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu529Phe Conflicting Single submitter
herpes simplex encephalitis, susceptibility to, 1

Predictors lean, ClinVar uncertain 285

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 285

TLR3 p.Ala185Val Uncertain significance Multiple submitters
susceptibility to HIV infection
TLR3 p.Ala549Thr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala795Val Uncertain significance Multiple submitters
immunodeficiency 83, susceptibility to viral infections
TLR3 p.Arg331Gln Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg809Lys Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg885Gln Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn141Asp Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn323Ser Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn516Asp Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn616Thr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp425Glu Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp47Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp524Gly Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp641His Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Cys37Arg Uncertain significance Multiple submitters
immunodeficiency 83, susceptibility to viral infections
TLR3 p.Gln96Arg Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly165Arg Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly320Arg Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly631Arg Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His129Arg Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His739Asn Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His819Tyr Uncertain significance Multiple submitters
TLR3 p.His833Tyr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His904Tyr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile338Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile510Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile708Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile848Leu Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile848Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu447His Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu722Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Lys163Thr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe224Tyr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Pro99Ala Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser24Phe Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser337Asn Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser339Ala Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser372Asn Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser500Pro Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser562Pro Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser775Tyr Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr151Ile Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr263Ala Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr54Lys Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr59Asn Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr86Ala Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Tyr283Cys Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Tyr383Phe Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Val720Ile Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Val736Ile Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala219Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala341Asp Uncertain significance Single submitter
TLR3 p.Ala426Val Uncertain significance Single submitter
TLR3 p.Ala477Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala491Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala519Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala69Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala802Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ala888Thr Uncertain significance Single submitter
TLR3 p.Arg251Gln Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg251Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg251Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg251Trp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg325Trp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg394Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg488Gln Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg488Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg506His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg643His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg64Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg64Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg729Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg749Gly Uncertain significance Single submitter
TLR3 p.Arg791Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg811Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg890Cys Uncertain significance Single submitter
TLR3 p.Arg890His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn180Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn196His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn252Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn275Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn284Ile Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn373His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn373Thr Uncertain significance Single submitter
TLR3 p.Asn380His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn380Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn388Thr Uncertain significance Single submitter
TLR3 p.Asn494Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn520Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn52Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn572Asp Uncertain significance Single submitter
TLR3 p.Asn57Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn607Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn659Asp Uncertain significance Single submitter
TLR3 p.Asn659Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn662His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn662Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn735Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn901Ile Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn901Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp116Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp153Ala Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp192Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp292Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp47Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp496Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp512Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp523Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp524Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp536Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp592Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp698Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp748Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp748Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp81Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Cys21Arg Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln174Glu Uncertain significance Single submitter
TLR3 p.Gln174His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln232His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln336Arg Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln470Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln753Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln753Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln894Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu211Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu211Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu358Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu434Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu446Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu460Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu570Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu576Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu639Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu663Gln Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu670Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu726Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu746Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu772Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu780Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly13Ala Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly13Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly13Cys Uncertain significance Single submitter
TLR3 p.Gly225Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly320Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly560Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly685Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly727Ala Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly796Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly898Glu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His156Arg Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1

Predictors split 52

The independent predictors disagree with each other — read with care.

TLR3 p.Ala839Asp Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg331Trp Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Cys875Ser Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly573Ser Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.His60Gln Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu199Phe Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu412Val Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr248Ala Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Val490Leu Uncertain significance Multiple submitters
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg643Cys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg867Gln Likely benign Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Arg890Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn413Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn417Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn507Lys Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asn596Ser Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp641Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Asp648His Uncertain significance Single submitter
TLR3 p.Gln113Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln538Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gln62Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Glu358Gly Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly221Val Uncertain significance Single submitter
TLR3 p.Gly743Asp Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Gly83Arg Uncertain significance Single submitter
TLR3 p.Ile250Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile346Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ile422Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu14Pro Uncertain significance Single submitter
TLR3 p.Leu176Phe Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu226Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu253Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu300Val Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Leu535Val Uncertain significance Single submitter
TLR3 p.Met642Thr Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe476Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe644Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe732Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe754Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Phe851Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Pro499Leu Uncertain significance Single submitter
TLR3 p.Pro602Ala Uncertain significance Single submitter
TLR3 p.Pro602Leu Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Pro646His Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser332Pro Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Ser339Cys Uncertain significance Single submitter
TLR3 p.Thr650Arg Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Thr664Asn Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Trp734Cys Uncertain significance Single submitter
TLR3 p.Tyr326Cys Uncertain significance Single submitter
TLR3 p.Val103Ala Uncertain significance Single submitter
herpes simplex encephalitis, susceptibility to, 1
TLR3 p.Val625Phe Uncertain significance Single submitter
immunodeficiency 83, susceptibility to viral infections

All TLR3 variants

Conflicting classifications of pathogenicity 7

c.441+3A>G Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg394Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg867Ter Single submitter immunodeficiency 83, susceptibility to viral infections
p.Glu663Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His319Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu297Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu529Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠

Benign 11

c.634-10C>A Multiple submitters herpes simplex encephalitis, susceptibility to, 1
c.-7C>A Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Arg643Ser Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Asn568= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Lys559= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Phe459= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ser737Thr Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Tyr307Asp Multiple submitters herpes simplex encephalitis, susceptibility to, 1
c.2486+50T>C Single submitter
c.2487-7dup Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu742Phe Single submitter herpes simplex encephalitis, susceptibility to, 1

Benign/Likely benign 10

c.634-12del Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ala888= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Asp280Asn Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.His739= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu204= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu243= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu412Phe Multiple submitters susceptibility to HIV infection
p.Leu852= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Phe851= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ser428= Multiple submitters herpes simplex encephalitis, susceptibility to, 1

Likely benign 163

c.634-11C>T Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ala185= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ala22= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Arg325= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Asn572= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Asp81= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Glu301= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.His129= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.His432Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.His548= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu154= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu15Trp Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu300= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Leu671= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Pro235= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ser332= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Ser776= Multiple submitters herpes simplex encephalitis, susceptibility to, 1
c.2486+14G>A Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2486+19A>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-14A>G Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-15C>T Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-17T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-18A>G Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-4T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.2487-8T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.441+12A>G Single submitter herpes simplex encephalitis, susceptibility to, 1
c.441+20T>G Single submitter
c.442-16T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.442-6C>G Single submitter herpes simplex encephalitis, susceptibility to, 1
c.442-7C>G Single submitter herpes simplex encephalitis, susceptibility to, 1
c.442-8C>T Single submitter herpes simplex encephalitis, susceptibility to, 1
c.633+9T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.634-10C>T Single submitter
c.634-12T>C Single submitter
c.634-18T>C Single submitter herpes simplex encephalitis, susceptibility to, 1
c.634-6C>T Single submitter
c.634-7C>T Single submitter herpes simplex encephalitis, susceptibility to, 1
c.634-8A>T Single submitter
c.-3A>G Single submitter
p.Ala120= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala491= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala519= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala68= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala795= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala835= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala839= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg251= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg643= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg65= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg867Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg885= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn181= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn275= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn291= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn373= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn474= Single submitter
p.Asn515= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn517= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn659= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn662= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn709= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn861= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp116Asn Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp348= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp48= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp575= Single submitter
p.Asp641= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp824= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Cys37= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Cys649= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gln167= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gln184His Single submitter
p.Glu110= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu175= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu239= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu580= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu746= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu755= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu794= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu841= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gly12= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gly12Arg Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gly13= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gly887= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gly887Ser Single submitter
p.His319= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His432= Single submitter
p.His539= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His565= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His665= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His724= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His834= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile150= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile193= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile346= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile461= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile555= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile566= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile591= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile8= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile803= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu111= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu130= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu176= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu202= Single submitter
p.Leu245= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu255= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu260= Single submitter
p.Leu269= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu271= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu305= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu393= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu487= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu535= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu542= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu561= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu567= Single submitter
p.Leu58= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu593= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu612= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu615= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu617= Single submitter
p.Leu637= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu722= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu788= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu80= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu800= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu864= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu866= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys137= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys272= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys345= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys831= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe630= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe634= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe798= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Pro298= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Pro46= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Pro669= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ser24= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ser571= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ser624= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr123= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr126= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr151= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr263= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr266= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr391= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr59= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr650= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr693= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Thr751= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Tyr302= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Tyr383= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Tyr465= Single submitter
p.Tyr756= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Tyr764= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val30= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val324= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val55= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val579= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val610= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Val658= Single submitter herpes simplex encephalitis, susceptibility to, 1

Uncertain significance 398

Showing the top 300 by review status; the full set is in the sitemap.

p.Ala185Val Multiple submitters susceptibility to HIV infection ⚠
p.Ala549Thr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala795Val Multiple submitters immunodeficiency 83, susceptibility to viral infections ⚠
p.Ala839Asp Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg331Gln Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg331Trp Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg809Lys Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg885Gln Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn141Asp Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn323Ser Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn516Asp Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn616Thr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp425Glu Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp47Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp524Gly Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp641His Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Cys37Arg Multiple submitters immunodeficiency 83, susceptibility to viral infections ⚠
p.Cys875Ser Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln753Ter Multiple submitters herpes simplex encephalitis, susceptibility to, 1
p.Gln96Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly165Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly320Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly573Ser Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly631Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His129Arg Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His60Gln Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His739Asn Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His819Tyr Multiple submitters ⚠
p.His833Tyr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His904Tyr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile338Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile510Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile708Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile848Leu Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile848Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu199Phe Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu412Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu447His Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu722Val Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys163Thr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe224Tyr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe798fs Multiple submitters immunodeficiency 83, susceptibility to viral infections
p.Pro554Ser Multiple submitters immunodeficiency 83, susceptibility to viral infections
p.Pro99Ala Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser24Phe Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser337Asn Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser339Ala Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser372Asn Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser500Pro Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser562Pro Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ser775Tyr Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr151Ile Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr248Ala Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr263Ala Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr54Lys Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr59Asn Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Thr86Ala Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Tyr283Cys Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Tyr383Phe Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Val490Leu Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Val720Ile Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Val736Ile Multiple submitters herpes simplex encephalitis, susceptibility to, 1 ⚠
c.441+1G>T Single submitter herpes simplex encephalitis, susceptibility to, 1
c.442-3C>T Single submitter herpes simplex encephalitis, susceptibility to, 1
c.633+136G>T Single submitter hepatitis C virus, susceptibility to
p.Ala219Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala341Asp Single submitter ⚠
p.Ala426Val Single submitter ⚠
p.Ala477Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala491Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala519Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala69Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala757fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ala802Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ala888fs Single submitter immunodeficiency 83, susceptibility to viral infections
p.Ala888Thr Single submitter ⚠
p.Ala896Val Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg251Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg251Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg251Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg251Trp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg325Trp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg394Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg394Ter Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg488Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg488Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg488Ter Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg506His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg506Leu Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg643Cys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg643His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg64Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg64Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg729Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg749Gly Single submitter ⚠
p.Arg749Ter Single submitter
p.Arg791Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg811Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg885Trp Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Arg890Cys Single submitter ⚠
p.Arg890His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Arg890Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn180Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn196fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn196His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn229Lys Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn252Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn275Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn284Ile Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn373His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn373Thr Single submitter ⚠
p.Asn380His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn380Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn388Thr Single submitter ⚠
p.Asn413Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn417Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn466del Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn494Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn507Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn520Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn52Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn572Asp Single submitter ⚠
p.Asn57Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn596Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn607Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn659Asp Single submitter ⚠
p.Asn659Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn662His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn662Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn735Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn901fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asn901Ile Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asn901Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp116Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp153Ala Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp192Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp292Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp36_Thr43del Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Asp47Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp496Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp512Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp523Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp524Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp536Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp592Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp641Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp648His Single submitter ⚠
p.Asp698Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp748Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp748Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp81Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Asp857Asn Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Cys21Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln113fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gln113Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln167Ter Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gln174Glu Single submitter ⚠
p.Gln174His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln232His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln336Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln470Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln538Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln62Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln753Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln753Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gln894= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Gln894Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu190_Leu191insGlu Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu211Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu211Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu358Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu358Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu434Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu446Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu460Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu570Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu576Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu639Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu663Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu670fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Glu670Gly Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu726Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu746Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu772Lys Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Glu780Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly13Ala Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly13Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly13Cys Single submitter ⚠
p.Gly13fs Single submitter
p.Gly221Val Single submitter ⚠
p.Gly225Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly320Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly560Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly685Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly727Ala Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly743Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly796Asp Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Gly83Arg Single submitter ⚠
p.Gly898Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His156Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His218Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His312Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His406Tyr Single submitter ⚠
p.His432_Leu433insTer Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His563Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His563fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His684Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His762Asn Single submitter herpes simplex encephalitis, susceptibility to, 1
p.His819Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His820Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His833Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His834Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His862Tyr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His874Tyr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His891Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.His904Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile138Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile150Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile250Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile346Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile346Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile379Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile411Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile422Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile518Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile518Val Single submitter ⚠
p.Ile521Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile53Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile53Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile622Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile719Thr Single submitter ⚠
p.Ile723Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile760Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile813Thr Single submitter ⚠
p.Ile840Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile848Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile855Phe Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Ile87Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Ile87Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu14fs Single submitter
p.Leu14Pro Single submitter ⚠
p.Leu176Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu226Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu253Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu300Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu313Trp Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu318fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu318Met Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu340Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu343Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu354Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu381fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu381Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu393Met Single submitter ⚠
p.Leu396Ser Single submitter ⚠
p.Leu438Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu440Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu526Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu535Val Single submitter ⚠
p.Leu564Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu588Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu5fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Leu612Pro Single submitter ⚠
p.Leu690Ile Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu704Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu721Phe Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu800Pro Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu844Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu864Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu893Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Leu98His Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys139Gln Single submitter TLR3-related disorder ⚠
p.Lys139Ter Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys147= Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys210Glu Single submitter ⚠
p.Lys421Glu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys493Arg Single submitter TLR3-related disorder ⚠
p.Lys583Gln Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys613Arg Single submitter ⚠
p.Lys619fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys628Asn Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys628del Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Lys697Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys872Arg Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Lys89Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met100Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met100Val Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met131Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met1Val Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Met642Thr Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met870Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Met870Val Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe17Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe322fs Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe351Ile Single submitter herpes simplex encephalitis, susceptibility to, 1
p.Phe375Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe459Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe476Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe644Leu Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠
p.Phe691Ser Single submitter herpes simplex encephalitis, susceptibility to, 1 ⚠