Sugi Variant

Sugi Variant/TRIM37

TRIM37 — 816 ClinVar variants

All ClinVar germline TRIM37 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 177 flagged for review →

41 Pathogenic · 16 Pathogenic/Likely pathogenic · 55 Likely pathogenic · 18 Conflicting · 40 Benign · 12 Benign/Likely benign · 411 Likely benign · 223 Uncertain significance

Full TRIM37 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 177

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 5

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 141

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 31

The independent predictors disagree with each other — read with care.

All TRIM37 variants

Pathogenic 41

Pathogenic/Likely pathogenic 16

Likely pathogenic 55

Conflicting classifications of pathogenicity 18

Benign 40

Benign/Likely benign 12

Likely benign 411

Showing the top 300 by review status; the full set is in the sitemap.

Uncertain significance 223