WNK3 — 274 ClinVar variants
All ClinVar germline WNK3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 201 flagged for review →
8 Pathogenic · 3 Likely pathogenic · 12 Conflicting · 13 Benign · 35 Likely benign · 203 Uncertain significance
Full WNK3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 201
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors vs ClinVar 1
ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.
-
WNK3 p.Glu607Val
Pathogenic
No assertion criteria
neurodevelopmental disorder
Predictors agree, ClinVar conflicts 11
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
- WNK3 p.Ala1746Val Conflicting Single submitter
- WNK3 p.Ala687Ser Conflicting Single submitter
- WNK3 p.Gln1179Glu Conflicting Single submitter
- WNK3 p.Gln262His Conflicting Single submitter
- WNK3 p.Glu1501Lys Conflicting Single submitter
- WNK3 p.Glu23Asp Conflicting Single submitter
- WNK3 p.Lys1374Arg Conflicting Single submitter
- WNK3 p.Pro1777Ser Conflicting Single submitter
-
WNK3 p.Thr1553Ile
Conflicting
Single submitter
Prieto syndrome
- WNK3 p.Val1739Ile Conflicting Single submitter
- WNK3 p.Val713Ile Conflicting Single submitter
Predictors lean, ClinVar uncertain 168
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 168
- WNK3 p.Ala827Asp Uncertain significance Multiple submitters
-
WNK3 p.Ala998Gly
Uncertain significance
Multiple submitters
Prieto syndrome
- WNK3 p.Arg487Trp Uncertain significance Multiple submitters
- WNK3 p.Gln956Leu Uncertain significance Multiple submitters
-
WNK3 p.Ile1355Thr
Uncertain significance
Multiple submitters
Prieto syndrome
- WNK3 p.Pro1725Leu Uncertain significance Multiple submitters
- WNK3 p.Pro902Ala Uncertain significance Multiple submitters
- WNK3 p.Val667Ile Uncertain significance Multiple submitters
- WNK3 p.Ala1036Val Uncertain significance Single submitter
- WNK3 p.Ala1223Thr Uncertain significance Single submitter
- WNK3 p.Ala1321Thr Uncertain significance Single submitter
- WNK3 p.Ala1327Val Uncertain significance Single submitter
- WNK3 p.Ala1444Asp Uncertain significance Single submitter
- WNK3 p.Ala1480Val Uncertain significance Single submitter
- WNK3 p.Ala157Ser Uncertain significance Single submitter
- WNK3 p.Ala1640Asp Uncertain significance Single submitter
- WNK3 p.Ala500Ser Uncertain significance Single submitter
- WNK3 p.Ala930Val Uncertain significance Single submitter
- WNK3 p.Arg1313Gln Uncertain significance Single submitter
- WNK3 p.Arg1313Trp Uncertain significance Single submitter
- WNK3 p.Arg1334Gln Uncertain significance Single submitter
- WNK3 p.Arg1565Cys Uncertain significance Single submitter
- WNK3 p.Arg1565His Uncertain significance Single submitter
- WNK3 p.Arg359Trp Uncertain significance Single submitter
- WNK3 p.Arg387His Uncertain significance Single submitter
- WNK3 p.Arg506Cys Uncertain significance Single submitter
- WNK3 p.Arg700Pro Uncertain significance Single submitter
- WNK3 p.Arg900Gln Uncertain significance Single submitter
-
WNK3 p.Arg929Cys
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Asn1030Asp Uncertain significance Single submitter
- WNK3 p.Asn1108Thr Uncertain significance Single submitter
- WNK3 p.Asn1262Ser Uncertain significance Single submitter
- WNK3 p.Asn1624Ile Uncertain significance Single submitter
- WNK3 p.Asn1791Ser Uncertain significance Single submitter
- WNK3 p.Asn371Ser Uncertain significance Single submitter
- WNK3 p.Asn445Ser Uncertain significance Single submitter
- WNK3 p.Asn86Ser Uncertain significance Single submitter
- WNK3 p.Asp1038Gly Uncertain significance Single submitter
- WNK3 p.Asp1222Ala Uncertain significance Single submitter
- WNK3 p.Asp1228Asn Uncertain significance Single submitter
- WNK3 p.Asp13Glu Uncertain significance Single submitter
- WNK3 p.Asp275Glu Uncertain significance Single submitter
- WNK3 p.Asp419Asn Uncertain significance Single submitter
- WNK3 p.Asp787His Uncertain significance Single submitter
- WNK3 p.Asp836Ala Uncertain significance Single submitter
- WNK3 p.Asp940Gly Uncertain significance Single submitter
- WNK3 p.Cys1426Ser Uncertain significance Single submitter
- WNK3 p.Cys1496Tyr Uncertain significance Single submitter
- WNK3 p.Cys254Gly Uncertain significance Single submitter
- WNK3 p.Cys511Phe Uncertain significance Single submitter
- WNK3 p.Gln1039Glu Uncertain significance Single submitter
-
WNK3 p.Gln108Glu
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Gln1415Arg Uncertain significance Single submitter
- WNK3 p.Gln1636Arg Uncertain significance Single submitter
- WNK3 p.Gln1741His Uncertain significance Single submitter
- WNK3 p.Gln28Arg Uncertain significance Single submitter
- WNK3 p.Gln520His Uncertain significance Single submitter
- WNK3 p.Gln605His Uncertain significance Single submitter
- WNK3 p.Gln745His Uncertain significance Single submitter
- WNK3 p.Gln815Arg Uncertain significance Single submitter
- WNK3 p.Glu1023Lys Uncertain significance Single submitter
- WNK3 p.Glu1213Lys Uncertain significance Single submitter
- WNK3 p.Glu1427Asp Uncertain significance Single submitter
- WNK3 p.Glu1492Lys Uncertain significance Single submitter
- WNK3 p.Glu1561Asp Uncertain significance Single submitter
- WNK3 p.Glu1682Ala Uncertain significance Single submitter
-
WNK3 p.Glu41Gly
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Gly1663Arg Uncertain significance Single submitter
- WNK3 p.Gly1663Glu Uncertain significance Single submitter
- WNK3 p.Gly629Arg Uncertain significance Single submitter
- WNK3 p.Gly741Trp Uncertain significance Single submitter
- WNK3 p.His546Arg Uncertain significance Single submitter
- WNK3 p.His559Arg Uncertain significance Single submitter
- WNK3 p.His819Tyr Uncertain significance Single submitter
- WNK3 p.His821Gln Uncertain significance Single submitter
- WNK3 p.Ile1002Val Uncertain significance Single submitter
- WNK3 p.Ile1619Met Uncertain significance Single submitter
- WNK3 p.Ile1667Leu Uncertain significance Single submitter
- WNK3 p.Ile1667Val Uncertain significance Single submitter
- WNK3 p.Ile216Val Uncertain significance Single submitter
- WNK3 p.Ile396Val Uncertain significance Single submitter
- WNK3 p.Ile810Val Uncertain significance Single submitter
- WNK3 p.Leu1260Ile Uncertain significance Single submitter
- WNK3 p.Leu1456Phe Uncertain significance Single submitter
- WNK3 p.Leu1596Val Uncertain significance Single submitter
- WNK3 p.Leu1622Trp Uncertain significance Single submitter
- WNK3 p.Leu276Arg Uncertain significance Single submitter
- WNK3 p.Leu503Trp Uncertain significance Single submitter
- WNK3 p.Lys124Arg Uncertain significance Single submitter
- WNK3 p.Lys1261Arg Uncertain significance Single submitter
- WNK3 p.Lys1377Glu Uncertain significance Single submitter
- WNK3 p.Lys1407Glu Uncertain significance Single submitter
- WNK3 p.Lys1458Glu Uncertain significance Single submitter
- WNK3 p.Lys498Gln Uncertain significance Single submitter
- WNK3 p.Lys935Thr Uncertain significance Single submitter
- WNK3 p.Met1219Leu Uncertain significance Single submitter
- WNK3 p.Met1300Val Uncertain significance Single submitter
- WNK3 p.Met1781Ile Uncertain significance Single submitter
- WNK3 p.Met770Val Uncertain significance Single submitter
- WNK3 p.Phe1037Ser Uncertain significance Single submitter
- WNK3 p.Phe1361Leu Uncertain significance Single submitter
- WNK3 p.Phe1439Cys Uncertain significance Single submitter
- WNK3 p.Phe1592Ser Uncertain significance Single submitter
- WNK3 p.Phe822Leu Uncertain significance Single submitter
- WNK3 p.Pro1071Arg Uncertain significance Single submitter
- WNK3 p.Pro1306Ser Uncertain significance Single submitter
- WNK3 p.Pro1343Ser Uncertain significance Single submitter
- WNK3 p.Pro1390Arg Uncertain significance Single submitter
- WNK3 p.Pro1694Leu Uncertain significance Single submitter
- WNK3 p.Pro1728Leu Uncertain significance Single submitter
- WNK3 p.Pro1730Ser Uncertain significance Single submitter
- WNK3 p.Pro499Leu Uncertain significance Single submitter
- WNK3 p.Pro556Arg Uncertain significance Single submitter
- WNK3 p.Pro639Leu Uncertain significance Single submitter
-
WNK3 p.Pro8Ser
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Pro906Arg Uncertain significance Single submitter
- WNK3 p.Ser1154Phe Uncertain significance Single submitter
- WNK3 p.Ser1198Leu Uncertain significance Single submitter
- WNK3 p.Ser1331Thr Uncertain significance Single submitter
- WNK3 p.Ser1423Arg Uncertain significance Single submitter
- WNK3 p.Ser1423Ile Uncertain significance Single submitter
- WNK3 p.Ser1485Thr Uncertain significance Single submitter
- WNK3 p.Ser1493Arg Uncertain significance Single submitter
- WNK3 p.Ser1572Ile Uncertain significance Single submitter
- WNK3 p.Ser47Cys Uncertain significance Single submitter
- WNK3 p.Ser49Cys Uncertain significance Single submitter
- WNK3 p.Ser798Thr Uncertain significance Single submitter
- WNK3 p.Ser854Tyr Uncertain significance Single submitter
- WNK3 p.Ser951Arg Uncertain significance Single submitter
- WNK3 p.Ser976Asn Uncertain significance Single submitter
- WNK3 p.Ser980Phe Uncertain significance Single submitter
- WNK3 p.Thr1043Pro Uncertain significance Single submitter
- WNK3 p.Thr1066Ser Uncertain significance Single submitter
- WNK3 p.Thr1085Ala Uncertain significance Single submitter
- WNK3 p.Thr1091Ile Uncertain significance Single submitter
- WNK3 p.Thr1138Ile Uncertain significance Single submitter
- WNK3 p.Thr1152Ala Uncertain significance Single submitter
- WNK3 p.Thr1181Ser Uncertain significance Single submitter
- WNK3 p.Thr11Ala Uncertain significance Single submitter
- WNK3 p.Thr1297Ile Uncertain significance Single submitter
- WNK3 p.Thr1387Ile Uncertain significance Single submitter
-
WNK3 p.Thr1428Asn
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Thr1574Ser Uncertain significance Single submitter
- WNK3 p.Thr1696Ala Uncertain significance Single submitter
- WNK3 p.Thr1696Asn Uncertain significance Single submitter
- WNK3 p.Thr1760Ile Uncertain significance Single submitter
- WNK3 p.Thr1786Ser Uncertain significance Single submitter
- WNK3 p.Thr34Arg Uncertain significance Single submitter
- WNK3 p.Thr753Ala Uncertain significance Single submitter
- WNK3 p.Thr834Ala Uncertain significance Single submitter
Predictors split 21
The independent predictors disagree with each other — read with care.
- WNK3 p.Arg1599His Uncertain significance Multiple submitters
- WNK3 p.Arg1281Trp Conflicting Single submitter
- WNK3 p.Arg1567Trp Uncertain significance Single submitter
- WNK3 p.Arg1588Gln Uncertain significance Single submitter
- WNK3 p.Arg1597Gln Uncertain significance Single submitter
-
WNK3 p.Arg190Lys
Uncertain significance
Single submitter
Prieto syndrome
- WNK3 p.Asp150Glu Uncertain significance Single submitter
- WNK3 p.Gly219Ala Uncertain significance Single submitter
- WNK3 p.Ile151Val Uncertain significance Single submitter
- WNK3 p.Ile386Val Uncertain significance Single submitter
- WNK3 p.Leu1117Phe Uncertain significance Single submitter
- WNK3 p.Lys390Gln Uncertain significance Single submitter
- WNK3 p.Met1520Thr Uncertain significance Single submitter
- WNK3 p.Met758Ile Uncertain significance Single submitter
- WNK3 p.Pro1586Arg Uncertain significance Single submitter
- WNK3 p.Thr237Met Uncertain significance Single submitter
- WNK3 p.Val329Ile Uncertain significance Single submitter
- WNK3 p.Val751Leu Uncertain significance Single submitter
- WNK3 p.Val759Ile Uncertain significance Single submitter
- WNK3 p.Val777Phe Uncertain significance Single submitter
- WNK3 p.Val795Met Likely benign Single submitter
All WNK3 variants
Pathogenic 8
- p.Glu1660Ter Single submitter
- p.Gly410Ter Single submitter Prieto syndrome
- c.1089+1G>A No assertion criteria Prieto syndrome
- c.538-2A>G No assertion criteria neurodevelopmental disorder
- p.Arg241Ter No assertion criteria Prieto syndrome
- p.Glu607Val No assertion criteria neurodevelopmental disorder ⚠
- p.Leu300Ser No assertion criteria Prieto syndrome
- p.Pro204Arg No assertion criteria Prieto syndrome
Likely pathogenic 3
- p.Arg1334fs Single submitter Delayed speech and language development
- p.Gln388Ter Single submitter
- p.Gly1466_Gln1468delinsGluGlu Single submitter
Conflicting classifications of pathogenicity 12
- p.Ala1746Val Single submitter ⚠
- p.Ala687Ser Single submitter ⚠
- p.Arg1281Trp Single submitter ⚠
- p.Gln1179Glu Single submitter ⚠
- p.Gln262His Single submitter ⚠
- p.Glu1501Lys Single submitter ⚠
- p.Glu23Asp Single submitter ⚠
- p.Lys1374Arg Single submitter ⚠
- p.Pro1777Ser Single submitter ⚠
- p.Thr1553Ile Single submitter Prieto syndrome ⚠
- p.Val1739Ile Single submitter ⚠
- p.Val713Ile Single submitter ⚠
Benign 13
- p.Gln704His Multiple submitters
- p.Glu913= Multiple submitters
- p.Gly723= Multiple submitters
- p.Ile946Thr Multiple submitters
- p.Pro530= Multiple submitters
- p.Pro719= Multiple submitters
- c.3652-54TTTGT[10] Single submitter
- c.3652-54TTTGT[11] Single submitter
- c.3652-54TTTGT[12] Single submitter
- c.3652-54TTTGT[6] Single submitter
- c.3652-54TTTGT[7] Single submitter
- p.Pro1413= Single submitter
- p.Val413= Single submitter
Likely benign 35
- c.4015-4T>C Multiple submitters
- p.Ser75Ala Multiple submitters
- p.Thr66Met Multiple submitters
- c.2102+7A>G Single submitter
- c.2523+8C>A Single submitter
- c.4015-9A>G Single submitter
- p.Ala1305Val Single submitter
- p.Ala1506Val Single submitter
- p.Ala1748Val Single submitter
- p.Ala1769Thr Single submitter
- p.Ala531Thr Single submitter
- p.Ala571Thr Single submitter
- p.Ala781Val Single submitter
- p.Ala896= Single submitter
- p.Arg507Ser Single submitter
- p.Arg929His Single submitter
- p.Asn1409= Single submitter
- p.Asn1791= Single submitter
- p.Gln1174= Single submitter
- p.Gln553Glu Single submitter
- p.Glu73= Single submitter
- p.Glu883Gly Single submitter
- p.Gly1227= Single submitter
- p.His1217Tyr Single submitter
- p.Ile1710= Single submitter
- p.Ile833Val Single submitter
- p.Pro1774= Single submitter
- p.Pro604Leu Single submitter
- p.Ser1723Pro Single submitter
- p.Ser1788Pro Single submitter
- p.Ser999Gly Single submitter
- p.Thr671Ile Single submitter
- p.Thr708Ser Single submitter
- p.Val53Ile Single submitter
- p.Val795Met Single submitter ⚠
Uncertain significance 203
- p.Ala827Asp Multiple submitters ⚠
- p.Ala998Gly Multiple submitters Prieto syndrome ⚠
- p.Arg1599His Multiple submitters ⚠
- p.Arg487Trp Multiple submitters ⚠
- p.Gln956Leu Multiple submitters ⚠
- p.Ile1355Thr Multiple submitters Prieto syndrome ⚠
- p.Pro1725Leu Multiple submitters ⚠
- p.Pro902Ala Multiple submitters ⚠
- p.Val667Ile Multiple submitters ⚠
- c.1399-5T>G Single submitter
- c.4870+1G>A Single submitter
- c.537+5871C>T Single submitter Prieto syndrome
- p.Ala1036Val Single submitter ⚠
- p.Ala1223Thr Single submitter ⚠
- p.Ala1321Thr Single submitter ⚠
- p.Ala1327Val Single submitter ⚠
- p.Ala1444Asp Single submitter ⚠
- p.Ala1480Val Single submitter ⚠
- p.Ala157Ser Single submitter ⚠
- p.Ala1640Asp Single submitter ⚠
- p.Ala500Ser Single submitter ⚠
- p.Ala930Val Single submitter ⚠
- p.Arg1313Gln Single submitter ⚠
- p.Arg1313Trp Single submitter ⚠
- p.Arg1334Gln Single submitter ⚠
- p.Arg1565Cys Single submitter ⚠
- p.Arg1565His Single submitter ⚠
- p.Arg1567Trp Single submitter ⚠
- p.Arg1588Gln Single submitter ⚠
- p.Arg1597Gln Single submitter ⚠
- p.Arg190Lys Single submitter Prieto syndrome ⚠
- p.Arg359Trp Single submitter ⚠
- p.Arg387His Single submitter ⚠
- p.Arg506Cys Single submitter ⚠
- p.Arg700Pro Single submitter ⚠
- p.Arg900Gln Single submitter ⚠
- p.Arg929Cys Single submitter Prieto syndrome ⚠
- p.Asn1030Asp Single submitter ⚠
- p.Asn1108Thr Single submitter ⚠
- p.Asn1262Ser Single submitter ⚠
- p.Asn1624Ile Single submitter ⚠
- p.Asn1791Ser Single submitter ⚠
- p.Asn371Ser Single submitter ⚠
- p.Asn445Ser Single submitter ⚠
- p.Asn768del Single submitter
- p.Asn86Ser Single submitter ⚠
- p.Asp1038Gly Single submitter ⚠
- p.Asp1222Ala Single submitter ⚠
- p.Asp1228Asn Single submitter ⚠
- p.Asp13Glu Single submitter ⚠
- p.Asp150Glu Single submitter ⚠
- p.Asp1524Val Single submitter
- p.Asp275Glu Single submitter ⚠
- p.Asp419Asn Single submitter ⚠
- p.Asp787His Single submitter ⚠
- p.Asp836Ala Single submitter ⚠
- p.Asp940Gly Single submitter ⚠
- p.Cys1426Ser Single submitter ⚠
- p.Cys1496Tyr Single submitter ⚠
- p.Cys254Gly Single submitter ⚠
- p.Cys511Phe Single submitter ⚠
- p.Gln1039Glu Single submitter ⚠
- p.Gln108fs Single submitter Prieto syndrome
- p.Gln108Glu Single submitter Prieto syndrome ⚠
- p.Gln1415Arg Single submitter ⚠
- p.Gln1636Arg Single submitter ⚠
- p.Gln1741His Single submitter ⚠
- p.Gln28Arg Single submitter ⚠
- p.Gln520His Single submitter ⚠
- p.Gln605His Single submitter ⚠
- p.Gln745His Single submitter ⚠
- p.Gln815Arg Single submitter ⚠
- p.Glu1023Lys Single submitter ⚠
- p.Glu1213Lys Single submitter ⚠
- p.Glu1384_Thr1387del Single submitter
- p.Glu1427Asp Single submitter ⚠
- p.Glu1492Lys Single submitter ⚠
- p.Glu1561Asp Single submitter ⚠
- p.Glu1682Ala Single submitter ⚠
- p.Glu41Gly Single submitter Prieto syndrome ⚠
- p.Gly1663Arg Single submitter ⚠
- p.Gly1663Glu Single submitter ⚠
- p.Gly219Ala Single submitter ⚠
- p.Gly629Arg Single submitter ⚠
- p.Gly741Trp Single submitter ⚠
- p.His546Arg Single submitter ⚠
- p.His559Arg Single submitter ⚠
- p.His819Tyr Single submitter ⚠
- p.His821Gln Single submitter ⚠
- p.Ile1002Val Single submitter ⚠
- p.Ile151Val Single submitter ⚠
- p.Ile1619Met Single submitter ⚠
- p.Ile1667Leu Single submitter ⚠
- p.Ile1667Val Single submitter ⚠
- p.Ile216Val Single submitter ⚠
- p.Ile386Val Single submitter ⚠
- p.Ile396Val Single submitter ⚠
- p.Ile810Val Single submitter ⚠
- p.Leu1117Phe Single submitter ⚠
- p.Leu1260Ile Single submitter ⚠
- p.Leu1456Phe Single submitter ⚠
- p.Leu1596Val Single submitter ⚠
- p.Leu1622Trp Single submitter ⚠
- p.Leu276Arg Single submitter ⚠
- p.Leu503Trp Single submitter ⚠
- p.Lys124Arg Single submitter ⚠
- p.Lys1261Arg Single submitter ⚠
- p.Lys1377Glu Single submitter ⚠
- p.Lys1407Glu Single submitter ⚠
- p.Lys1458Glu Single submitter ⚠
- p.Lys1643Thr Single submitter
- p.Lys277= Single submitter
- p.Lys390Gln Single submitter ⚠
- p.Lys498Gln Single submitter ⚠
- p.Lys935Thr Single submitter ⚠
- p.Met1219Leu Single submitter ⚠
- p.Met1300Val Single submitter ⚠
- p.Met1520Thr Single submitter ⚠
- p.Met1781Ile Single submitter ⚠
- p.Met1Val Single submitter
- p.Met758Ile Single submitter ⚠
- p.Met770Val Single submitter ⚠
- p.Phe1037Ser Single submitter ⚠
- p.Phe1361del Single submitter
- p.Phe1361Leu Single submitter ⚠
- p.Phe1439Cys Single submitter ⚠
- p.Phe1592Ser Single submitter ⚠
- p.Phe822Leu Single submitter ⚠
- p.Pro1071Arg Single submitter ⚠
- p.Pro1306Ser Single submitter ⚠
- p.Pro1343Ser Single submitter ⚠
- p.Pro1390Arg Single submitter ⚠
- p.Pro1586Arg Single submitter ⚠
- p.Pro1694Leu Single submitter ⚠
- p.Pro1728Leu Single submitter ⚠
- p.Pro1730Ser Single submitter ⚠
- p.Pro270del Single submitter
- p.Pro499Leu Single submitter ⚠
- p.Pro556Arg Single submitter ⚠
- p.Pro639Leu Single submitter ⚠
- p.Pro8Ser Single submitter Prieto syndrome ⚠
- p.Pro906Arg Single submitter ⚠
- p.Ser1154Phe Single submitter ⚠
- p.Ser1198Leu Single submitter ⚠
- p.Ser1285Asn Single submitter
- p.Ser1331Thr Single submitter ⚠
- p.Ser1423Arg Single submitter ⚠
- p.Ser1423Ile Single submitter ⚠
- p.Ser1485Thr Single submitter ⚠
- p.Ser1493Arg Single submitter ⚠
- p.Ser1572Ile Single submitter ⚠
- p.Ser47Cys Single submitter ⚠
- p.Ser49Cys Single submitter ⚠
- p.Ser798Thr Single submitter ⚠
- p.Ser854Tyr Single submitter ⚠
- p.Ser951Arg Single submitter ⚠
- p.Ser976Asn Single submitter ⚠
- p.Ser980Phe Single submitter ⚠
- p.Ter1801Arg Single submitter
- p.Thr1043Pro Single submitter ⚠
- p.Thr1066Ser Single submitter ⚠
- p.Thr1085Ala Single submitter ⚠
- p.Thr1091Ile Single submitter ⚠
- p.Thr1138Ile Single submitter ⚠
- p.Thr1152Ala Single submitter ⚠
- p.Thr1158_Val1160del Single submitter
- p.Thr1181Ser Single submitter ⚠
- p.Thr11Ala Single submitter ⚠
- p.Thr1297Ile Single submitter ⚠
- p.Thr1387Ile Single submitter ⚠
- p.Thr1428Asn Single submitter Prieto syndrome ⚠
- p.Thr1574Ser Single submitter ⚠
- p.Thr1696Ala Single submitter ⚠
- p.Thr1696Asn Single submitter ⚠
- p.Thr1760Ile Single submitter ⚠
- p.Thr1786Ser Single submitter ⚠
- p.Thr237Met Single submitter ⚠
- p.Thr34Arg Single submitter ⚠
- p.Thr753Ala Single submitter ⚠
- p.Thr834Ala Single submitter ⚠
- p.Thr878Ala Single submitter ⚠
- p.Thr884Ser Single submitter ⚠
- p.Thr981Ser Single submitter ⚠
- p.Tyr1005His Single submitter Prieto syndrome ⚠
- p.Tyr1232Phe Single submitter ⚠
- p.Tyr1396Phe Single submitter ⚠
- p.Tyr1734His Single submitter ⚠
- p.Tyr1742Cys Single submitter ⚠
- p.Tyr464His Single submitter ⚠
- p.Val1157Met Single submitter ⚠
- p.Val1381Ile Single submitter ⚠
- p.Val138Ile Single submitter ⚠
- p.Val1430Ile Single submitter ⚠
- p.Val329Ile Single submitter ⚠
- p.Val63Ala Single submitter ⚠
- p.Val751Leu Single submitter ⚠
- p.Val759Ile Single submitter ⚠
- p.Val777Phe Single submitter ⚠
- p.Val790Ala Single submitter
- p.Val804Ala Single submitter ⚠
- p.Val830Gly Single submitter ⚠
- p.Val963Glu Single submitter ⚠
- p.Ala1277Pro No assertion criteria WNK3-related condition ⚠