NEBL c.(?_1228
Uncertain significance
Single submitter
Classification
Uncertain significance
ClinVar
Review
Single submitter ★☆☆☆
ClinVar · 1 submitter
gnomAD v4.1
Rare
Computational evidence
| Protein change | ||
| Missense predictors do not apply to this variant type. |
Variant & gene context
- Gene
- NEBL
- Coding
- c.(?_1228
- MANE Select
- NM_006393
- Type
- Deletion
- Location
- chr10:None (GRCh38)
- Gene constraint
- LOEUF 1.036 · pLI <0.01 · ClinGen HI 0/3 (gnomAD)
- Structure
- AlphaFold pLDDT 62.00 · 1 PDB
Similar variants
- NEBL p.Asn23_Glu24del Uncertain significance ★★ same type
- NEBL p.Asn346fs Uncertain significance ★★ same type
- NEBL p.Gly81fs Uncertain significance ★★ same type
- NEBL p.Ile456fs Uncertain significance ★★ same type
- NEBL p.Ile93fs Uncertain significance ★★ same type
- NEBL p.Leu37fs Uncertain significance ★★ same type
- NEBL c.2519-2del Benign ★★ same type
- NEBL c.357+73457del Benign ★★ same type
Built on 18 open, versioned datasets — ClinVar, gnomAD, AlphaMissense, REVEL, ClinGen & more — plus Sugi Variant's own cross-source analysis. Source data 2026-01–2026-10, ClinVar 2026-10. Full sources & versions →
Cite Sugi Variant
Gür T. Sugi Variant: A Deterministic Per-Variant Germline Reference from a Knowledge Graph for Humans and AI Agents. 2026. doi:10.5281/zenodo.21509445. This variant: https://sugi.bio/variant/nebl-c-1228 (accessed [today's date]).
Preprint & method: sugi.bio/variant/method Machine-readable: this page as Markdown