SCHEMBL10000241

SCHEMBL10000241

Cc1ccc(C2CCC(C)CC2)s1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
ESR2 Q92731 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
ALDH1A1 P00352 6/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15448627 1.00 NPC1 (0.49) NPC1RAB9AESR2CHRM2CHRM4
SCHEMBL16661514 0.91
SCHEMBL19101171 0.90 NPC1 (0.41) NPC1RAB9AESR2CHRM2CHRM4
SCHEMBL17151014 0.90 NPC1 (0.41) NPC1RAB9AESR2CHRM2CHRM4
SCHEMBL17149564 0.90 NPC1 (0.41) NPC1RAB9AESR2CHRM2CHRM4
SCHEMBL8127649 0.80 HPGD (0.42) NPC1RAB9ACHRM2CHRM4CHRM5
SCHEMBL15448414 0.78 IDO1 (0.38) NPC1RAB9ACHRM2CHRM4CHRM5
SCHEMBL23879771 0.74 SLC6A2 (0.47) NPC1RAB9ACHRM2CHRM4CHRM5
SCHEMBL24164181 0.74 CHRM2 (0.38) NPC1RAB9ACHRM2CHRM4CHRM5
SCHEMBL15448359 0.74 ALDH1A1 (0.41) NPC1RAB9AESR2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed