Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | PDE4A | P27815 | 3/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879913 | 0.91 | MAPK1 (0.39) | MAPK1PDE10AAOC3CHRM3PDE4A | |
| SCHEMBL12457538 | 0.82 | MAPK1 (0.37) | MAPK1PDE10AAOC3CHRM3PDE4A | |
| SCHEMBL18511914 | 0.81 | ESR2 (0.44) | ESR2MAPK1PDK2PDK4HDAC4 | |
| SCHEMBL8984420 | 0.81 | ESR2 (0.48) | ESR2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL17972935 | 0.80 | L3MBTL1 (0.37) | MAPK1CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1332474 | 0.78 | MAPK1 (0.35) | MAPK1PDE10APDK2PDK4HDAC4 | |
| SCHEMBL11190323 | 0.78 | ESR2 (0.41) | ESR2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL10091188 | 0.78 | CHRM3 (0.35) | MAPK1PDE10AAOC3CHRM3PDE4A | |
| SCHEMBL11190329 | 0.78 | ESR2 (0.41) | ESR2CHRM3PDE4APDE4BPDE4C | |
| SCHEMBL18509357 | 0.77 | ESR2 (0.39) | ESR2PDE10ACHRM3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120262-A1 | COMPOUNDS AND METHODS FOR IMPROVING IMPAIRED ENDOGENOUS FIBRINOLYSIS USING HISTONE DEACETYLASE INHIBITORS | LARSSON PIA (SE) | 2012-09-13 | — | — | WO | disclosed |
| US-8158020-B2 | Liquid crystal element, optical path deflecting element, and image displaying apparatus | RICOH COMPANY, LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158020-B2 | Liquid crystal element, optical path deflecting element, and image displaying apparatus | RICOH COMPANY, LTD. (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20080204608-A1 | Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus | RICOH COMPANY, LTD. (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080204608-A1 | Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus | RICOH COMPANY, LTD. (JP) | 2008-08-28 | — | — | US | disclosed |