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L3MBTL1

Lethal(3)malignant brain tumor-like protein 1 · Q9Y468 · L3MBTL1 on Sugi Atlas →

2,671,747 patent compounds predicted against L3MBTL1, 1,411,996 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL9028 SCHEMBL9028 0.56 8/20
Doxycycline Anhydrous Doxycycline Anhydrous (SCHEMBL3156) 0.69 7/20
Doxycycline Anhydrous Doxycycline Anhydrous (SCHEMBL3155) 0.68 7/20
SCHEMBL9463 SCHEMBL9463 0.61 7/20
SCHEMBL4015 SCHEMBL4015 0.72 6/20
Methacycline Methacycline (SCHEMBL4014) 0.69 6/20
Methacycline Methacycline (SCHEMBL4016) 0.69 6/20
SCHEMBL9819 SCHEMBL9819 0.56 6/20
SCHEMBL3925 SCHEMBL3925 0.53 6/20
SCHEMBL6707 SCHEMBL6707 0.38 6/20
SCHEMBL6627 SCHEMBL6627 0.71 5/20
SCHEMBL4792 SCHEMBL4792 0.64 5/20
Nitroanilide Nitroanilide (SCHEMBL6001) 0.50 5/20
SCHEMBL1282 SCHEMBL1282 0.47 5/20
SCHEMBL2072 SCHEMBL2072 0.46 5/20
SCHEMBL6024 SCHEMBL6024 0.40 5/20
Cephapirin Cephapirin (SCHEMBL3205) 0.84 4/20
Oxytetracycline Oxytetracycline (SCHEMBL2898) 0.70 4/20
Oxytetracycline Oxytetracycline (SCHEMBL2899) 0.69 4/20
Chloroxine Chloroxine (SCHEMBL3350) 0.62 4/20

Clinical trials — most relevant to L3MBTL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
Lamivudine as a Novel Clinical Effort for Rett Syndrome PHASE2ENROLLING_BY_INVITATION
Safety Study of a Gene Transfer Vector for Children With Late Infantile Neuronal Ceroid Lipofuscinosis PHASE1COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome nanRECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Long Term Monitoring for Risk of Sudden Death nanCOMPLETED
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Sperm Epigenome in Hodgkin Lymphoma nanNOT_YET_RECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING
miRNA as a Growth Plate Marker After GH nanUNKNOWN
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Uncovering Genes Behind Cartilage Tumors and Vascular Anomalies Using Genomic Sequencing nanRECRUITING
Study of Constitutional Platelet Disease nanUNKNOWN
MicroRNAs and Cytokines in Peri-Implantitis Tissue nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
Viral and Epigenetic Influences in CRSwNP nanACTIVE_NOT_RECRUITING
Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage nanUNKNOWN
Immunophenotyping and Xist Gene in AML nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a L3MBTL1 binder may also engage these)

ProteinNameSimilarity
E1C2V1 — 1.000 E1C2V1 →
D3ZWK4 — 0.999 D3ZWK4 →
Q5DW34 — 0.996 Q5DW34 →
Q63553 — 0.996 Q63553 →
L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 0.996 landscape →
USP19 Ubiquitin carboxyl-terminal hydrolase 19 0.996 landscape →
Q76I79 — 0.996 Q76I79 →
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 0.995 landscape →
Q80UW3 — 0.995 Q80UW3 →
Q2PFD7 — 0.995 Q2PFD7 →
Q8CJE2 — 0.995 Q8CJE2 →
Q9BQK8 — 0.995 Q9BQK8 →
Q9H329 — 0.995 Q9H329 →
P56931 — 0.995 P56931 →
Q60700 — 0.995 Q60700 →
Q9Z0E3 — 0.995 Q9Z0E3 →
Q3UJD6 — 0.994 Q3UJD6 →
Q5BIR3 — 0.994 Q5BIR3 →
Q8BWQ5 — 0.994 Q8BWQ5 →
Q3V1D5 — 0.994 Q3V1D5 →
Q99PI4 — 0.994 Q99PI4 →
Q8WML3 — 0.994 Q8WML3 →
Q8BZ21 — 0.994 Q8BZ21 →
O95625 — 0.994 O95625 →
BRPF3 Bromodomain and PHD finger-containing protein 3 0.994 landscape →
Q99PI5 — 0.994 Q99PI5 →
A7MBB4 — 0.993 A7MBB4 →
A6QP06 — 0.993 A6QP06 →
Q6P1I6 — 0.993 Q6P1I6 →
A2A5N8 — 0.993 A2A5N8 →