SCHEMBL10000247

SCHEMBL10000247

Cc1ccc(-c2ccc(-c3ccc(C)nn3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.52
RAB9A P51151 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
LMNA P02545 3/20 0.52
NFKB1 P19838 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 5/20 0.45
POLB P06746 1/20 0.45
NOTUM Q6P988 1/20 0.45
ENPP3 O14638 1/20 0.44
ENPP1 P22413 1/20 0.44
MEN1 O00255 4/20 0.42
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000239 0.98 NPC1 (0.53) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051572 0.95 NPC1 (0.52) NPC1RAB9ASMN1; SMN2LMNANFKB1
Ammonia Solution, Strong SCHEMBL28862433 0.95 NPC1 (0.52) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051575 0.91 NPC1 (0.44) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL10000254 0.88 NPC1 (0.61) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051530 0.86 KDM1A (0.45) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051542 0.84 CCR1 (0.56) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051551 0.82 CCR1 (0.48) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051585 0.82 CCR1 (0.43) NPC1RAB9ASMN1; SMN2LMNANFKB1
SCHEMBL17051536 0.81 HPGDS (0.42) NPC1RAB9ASMN1; SMN2LMNANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed