SCHEMBL10000267

SCHEMBL10000267

C=CCCCc1ccc(-c2ccc(-c3ncc(CCCCCC)cn3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.62
MAPT P10636 4/20 0.62
SMN1; SMN2 Q16637 4/20 0.62
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 3/20 0.62
HSD17B10 Q99714 2/20 0.62
KDM4E B2RXH2 2/20 0.62
HPGD P15428 2/20 0.62
USP2 O75604 1/20 0.62
GAA P10253 1/20 0.62
RARB P10826 6/20 0.58
RARA P10276 1/20 0.47
MTOR P42345 1/20 0.47
NPC1 O15118 3/20 0.46
STAT3 P40763 1/20 0.46
ATM Q13315 1/20 0.46
THRA P10827 5/20 0.46
THRB P10828 5/20 0.46
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10341625 0.97 RAB9A (0.61) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9636394 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL8596123 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9637558 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9221975 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9227943 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9636397 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9229470 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL6665924 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A
SCHEMBL9636179 0.89 MAPT (0.77) RAB9AMAPTSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed
US-20080204608-A1 Liquid Crystal Element, Optical Path Deflecting Element, and Image Displaying Apparatus RICOH COMPANY, LTD. (JP) 2008-08-28 US disclosed