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RAB9A

Ras-related protein Rab-9A · P51151 · RAB9A on Sugi Atlas →

3,587,940 patent compounds predicted against RAB9A, 1,838,282 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL3925 SCHEMBL3925 0.53 9/20
SCHEMBL3777 SCHEMBL3777 0.37 9/20
SCHEMBL3979 SCHEMBL3979 0.70 8/20
SCHEMBL1672 SCHEMBL1672 0.51 8/20
Paclitaxel Paclitaxel (SCHEMBL3976) 1.00 7/20
SCHEMBL4805 SCHEMBL4805 0.69 7/20
SCHEMBL4792 SCHEMBL4792 0.64 7/20
SCHEMBL4746 SCHEMBL4746 0.50 7/20
SCHEMBL7492 SCHEMBL7492 0.46 7/20
SCHEMBL8475 SCHEMBL8475 0.45 7/20
Docetaxel Anhydrous Docetaxel Anhydrous (SCHEMBL4417) 0.86 6/20
Docetaxel Anhydrous Docetaxel Anhydrous (SCHEMBL4418) 0.86 6/20
Docetaxel Anhydrous Docetaxel Anhydrous (SCHEMBL4419) 0.86 6/20
Methyl Benzoate Methyl Benzoate (SCHEMBL7200) 0.67 6/20
Isoflavone Isoflavone (SCHEMBL8028) 0.66 6/20
SCHEMBL8211 SCHEMBL8211 0.56 6/20
SCHEMBL7158 SCHEMBL7158 0.54 6/20
SCHEMBL8602 SCHEMBL8602 0.51 6/20
SCHEMBL7014 SCHEMBL7014 0.47 6/20
SCHEMBL3813 SCHEMBL3813 0.45 6/20

Clinical trials — most relevant to RAB9A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK PHASE1/PHASE2RECRUITING
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC) PHASE2COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Identification of New Biomarkers of Insulin Resistance nanACTIVE_NOT_RECRUITING
Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial nanRECRUITING
Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease nanUNKNOWN
Fox BioNet Project: LRRK2-002 nanCOMPLETED
Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients nanRECRUITING
Parkinson's Families Project nanRECRUITING
Pubertal Development in Patients with RASopathies nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies nanRECRUITING
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING
Genetic Studies of Chronic Active Epstein-Barr Disease nanRECRUITING
Biomarker Research in Inherited Movement Disorders nanRECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Genotype-Phenotype Correlations of Late Infantile Neuronal Ceroid Lipofuscinosis nanCOMPLETED
Gene Analysis of Parkinson's Disease nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
RASopathy Biorepository nanRECRUITING
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Prevalence and Characterization of Pain in RASopathies nanUNKNOWN
A Multicentric European Study to Promote Clinical Trial Readiness for STXBP1-related Disorders nanRECRUITING
Consortium On Risk for Early-onset Parkinson's Disease (CORE PD) nanCOMPLETED
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN) nanRECRUITING
TECPR2 Observational Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a RAB9A binder may also engage these)

ProteinNameSimilarity
P24408 — 1.000 P24408 →
Q9R0M6 — 1.000 Q9R0M6 →
Q99P75 — 1.000 Q99P75 →
Q5R4W9 — 1.000 Q5R4W9 →
P93267 — 1.000 P93267 →
C8VQY7 — 0.999 C8VQY7 →
Q43463 — 0.999 Q43463 →
Q9C820 — 0.999 Q9C820 →
Q9NP90 — 0.998 Q9NP90 →
Q8BHH2 — 0.998 Q8BHH2 →
Q9C2L8 — 0.997 Q9C2L8 →
Q8BHD0 — 0.997 Q8BHD0 →
H9BW96 — 0.997 H9BW96 →
P31022 — 0.997 P31022 →
P09527 — 0.996 P09527 →
Q39573 — 0.996 Q39573 →
Q9LW76 — 0.996 Q9LW76 →
RAB39A Ras-related protein Rab-39A 0.996 landscape →
Q3T0F5 — 0.995 Q3T0F5 →
Q91YQ1 — 0.995 Q91YQ1 →
Q948K8 — 0.995 Q948K8 →
P63011 — 0.995 P63011 →
Q41640 — 0.994 Q41640 →
O24461 — 0.994 O24461 →
P25228 — 0.994 P25228 →
RAB29 Ras-related protein Rab-7L1 0.994 landscape →
O04157 — 0.994 O04157 →
P11023 — 0.994 P11023 →
Q9LS94 — 0.994 Q9LS94 →
P17610 — 0.994 P17610 →