Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387236 | 1.00 | NPC1 (0.67) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL13310847 | 1.00 | NPC1 (0.67) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10502311 | 0.95 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10000270 | 0.95 | NPC1 (0.73) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL13987904 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9235626 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9239737 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6017464 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9318472 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6017545 | 0.90 | NPC1 (0.71) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250338-A1 | COMPOUND AND LIQUID CRYSTAL COMPOSITION | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-08-10 | — | — | US | disclosed |
| US-20180216004-A1 | LOW BIREFRINGENCE FERROELECTRIC LIQUID CRYSTAL MIXTURES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-08-02 | — | — | US | disclosed |
| US-20140313468-A1 | LIQUID CRYSTAL DISPLAY ELEMENT | DIC CORPORATION (JP) | 2014-10-23 | — | — | US | disclosed |
| US-8158020-B2 | Liquid crystal element, optical path deflecting element, and image displaying apparatus | RICOH COMPANY, LTD. (JP) | 2012-04-17 | — | — | US | disclosed |