SCHEMBL10000273

SCHEMBL10000273

Cc1ccc(-c2nnc(-c3ccccc3)s2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
LMNA P02545 1/20 0.62
ALOX5 P09917 1/20 0.56
POLB P06746 2/20 0.55
SREBF2 Q12772 1/20 0.55
RAB9A P51151 5/20 0.53
NPC1 O15118 4/20 0.53
HPGD P15428 2/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
TDP1 Q9NUW8 2/20 0.48
S1PR1 P21453 1/20 0.47
S1PR3 Q99500 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CASP3 P42574 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000252 0.91 ALDH1A1 (0.72) ALDH1A1SMN1; SMN2LMNAALOX5POLB
SCHEMBL17948201 0.86 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAPOLBRAB9A
SCHEMBL9018567 0.86 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNAPOLBRAB9A
SCHEMBL2213286 0.84 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAPOLBRAB9A
SCHEMBL26194032 0.82 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAALOX5POLB
SCHEMBL12776861 0.81 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAALOX5POLB
SCHEMBL21346519 0.81 SMN1; SMN2 (0.60) ALDH1A1SMN1; SMN2LMNARAB9ANPC1
SCHEMBL738448 0.80 SMN1; SMN2 (0.64) ALDH1A1SMN1; SMN2LMNAALOX5POLB
SCHEMBL2421712 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAALOX5POLB
SCHEMBL28574866 0.80 HDAC6 (0.61) ALDH1A1SMN1; SMN2LMNARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11508927-B2 Organic electroluminescence device, preparation method thereof and display apparatus KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-11-22 US disclosed
US-20200203652-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, PREPARATION METHOD THEREOF AND DISPLAY APPARATUS KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2020-06-25 US disclosed
US-8158020-B2 Liquid crystal element, optical path deflecting element, and image displaying apparatus RICOH COMPANY, LTD. (JP) 2012-04-17 US disclosed