Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571901 | 1.00 | ADRB2 (0.42) | ADRB2ADRB1KDM1AALDH1A1CYP3A4 | |
| SCHEMBL31571902 | 1.00 | ADRB2 (0.42) | ADRB2ADRB1KDM1AALDH1A1CYP3A4 | |
| SCHEMBL9955892 | 0.80 | ADRB2 (0.42) | ADRB2KDM1ACYP3A4GLAPOLB | |
| SCHEMBL2098677 | 0.79 | CYP3A4 (0.36) | ADRB2ADRB1ALDH1A1CYP3A4POLB | |
| SCHEMBL10093727 | 0.79 | ADRB2 (0.45) | ADRB2ADRB1ALDH1A1CYP3A4GLA | |
| SCHEMBL29470926 | 0.79 | CYP3A4 (0.36) | ADRB2ADRB1ALDH1A1CYP3A4POLB | |
| SCHEMBL978692 | 0.78 | NOTUM (0.42) | KDM1AALDH1A1CYP3A4IDO1HTR3E | |
| SCHEMBL3240959 | 0.78 | ADRB2 (0.44) | ADRB2ADRB1ALDH1A1CYP3A4GLA | |
| SCHEMBL2434618 | 0.78 | CYP3A4 (0.56) | ADRB2ADRB1ALDH1A1CYP3A4GLA | |
| SCHEMBL720822 | 0.78 | KDM1A (0.38) | ADRB2KDM1AALDH1A1GLAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118026854-A | Preparation method of 2-chloro-6-trifluoromethyl aniline | 鹤壁市宝瑞德化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-113636919-B | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoroacetophenone | 上海恩氟佳科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-113636919-A | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoro acetophenone | 上海恩氟佳科技有限公司 | 2021-11-12 | — | — | CN | claimed |
| CN-119912402-A | FTO inhibitor and preparation method and application thereof | 中国科学院上海药物研究所 | 2025-05-02 | — | — | CN | disclosed |
| CN-118026854-A | Preparation method of 2-chloro-6-trifluoromethyl aniline | 鹤壁市宝瑞德化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-118026854-A | Preparation method of 2-chloro-6-trifluoromethyl aniline | 鹤壁市宝瑞德化工有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113636919-B | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoroacetophenone | 上海恩氟佳科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-113636919-B | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoroacetophenone | 上海恩氟佳科技有限公司 | 2023-10-24 | — | — | CN | disclosed |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2023-03-02 | — | — | US | disclosed |
| CN-113636919-A | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoro acetophenone | 上海恩氟佳科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| CN-113636919-A | Method for synthesizing 3-chloro-5-trifluoromethyl trifluoro acetophenone | 上海恩氟佳科技有限公司 | 2021-11-12 | — | — | CN | disclosed |
| EP-2183250-A1 | NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | Valeant Pharmaceuticals International, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| US-20090170885-A1 | NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 2009-07-02 | — | — | US | disclosed |
| EP-2061465-A2 | DERIVATIVES OF 4-(N-AZACYCLOALKYL) ANILIDES AS POTASSIUM CHANNEL MODULATORS | Valeant Pharmaceuticals International (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2009018466-A1 | NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| US-20080139610-A1 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators | VALEANT PHARMACEUTICALS NORTH AMERICA (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139610-A1 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators | VALEANT PHARMACEUTICALS NORTH AMERICA (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139610-A1 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators | VALEANT PHARMACEUTICALS NORTH AMERICA (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2008024398-A2 | DERIVATIVES OF 4-(N-AZACYCLOALKYL) ANILIDES AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2008-02-28 | — | — | WO | disclosed |
| WO-2008024398-A2 | DERIVATIVES OF 4-(N-AZACYCLOALKYL) ANILIDES AS POTASSIUM CHANNEL MODULATORS | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139610-A1 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators | KCNQ2, KCNQ1, KCNQ5 | ADRB2 1934/4885ADRB1 1277/4885KDM1A 165/4885 |
| US-20090170885-A1 | NAPHTHYRIDINE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | KCNJ11, KCNQ5, KCNJ1 | ADRB2 627/4885ADRB1 415/4885KDM1A 1124/4885 |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | ADRB2 87/4885ADRB1 48/4885KDM1A 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.