Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20313357 | 1.00 | TYR (0.42) | TYRSHBGESR1TRPV1CES2 | |
| SCHEMBL7170978 | 0.96 | TYR (0.39) | TYRSHBGESR1TRPV1CES2 | |
| SCHEMBL2033663 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL34981 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL29370365 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL2027319 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL2033866 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL6057474 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL14998827 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN | |
| SCHEMBL29370396 | 0.93 | SHBG (0.40) | TYRSHBGESR1CES2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093320-B2 | Compositions comprising polyphosphonates and additives that exhibit an advantageous combination of properties, and methods related thereto | FRX POLYMERS, INC. (US) | 2012-01-10 | — | — | US | disclosed |