Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3725858 | 0.89 | SIGMAR1 (0.57) | SIGMAR1GFERMAOBMAPTMAOA | |
| SCHEMBL13897016 | 0.87 | SIGMAR1 (0.58) | SIGMAR1GFERMAOBMAPTMAOA | |
| SCHEMBL9627913 | 0.87 | SIGMAR1 (0.66) | SIGMAR1GFERMAOBMAOAKCNH2 | |
| SCHEMBL5205808 | 0.84 | MAPT (0.49) | SIGMAR1MAOBMAPTTMEM97 | |
| SCHEMBL25047608 | 0.82 | SIGMAR1 (0.66) | SIGMAR1TMEM97THRATHRB | |
| SCHEMBL25046697 | 0.82 | TAAR1 (0.58) | SIGMAR1 | |
| SCHEMBL26985749 | 0.81 | SIGMAR1 (0.70) | SIGMAR1TMEM97 | |
| SCHEMBL13593460 | 0.81 | SIGMAR1 (0.54) | SIGMAR1GFERMAPTKCNH2THRA | |
| SCHEMBL9671108 | 0.79 | KCNH2 (0.57) | SIGMAR1KCNH2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5133086 | 0.79 | SIGMAR1 (0.47) | SIGMAR1KCNH2TMEM97THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-05-08 | — | — | US | disclosed |
| US-8629299-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-01-14 | — | — | US | disclosed |
| US-8629299-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2014-01-14 | — | — | US | disclosed |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| US-8445721-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-8445721-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
| US-8148575-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-8148575-B2 | Radiofluorinated compounds and their preparation | HAMMERSMITH IMANET LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | HAMMERSMITH IMANET LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | HAMMERSMITH IMANET LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
| WO-2007122488-A2 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | HAMMERSMITH IMANET LIMITED (GB) | 2007-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087379-A1 | Radiofluorinated Compounds and their Preparation | PSMA5, MPI, PSMA3 | SIGMAR1 1641/4885GFER 1938/4885MAOB 2050/4885 |
| US-20120171117-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | SIGMAR1 1641/4885GFER 1938/4885MAOB 2050/4885 |
| US-20140127130-A1 | Radiofluorinated compounds and their preparation | PSMA5, MPI, PSMA3 | SIGMAR1 1641/4885GFER 1938/4885MAOB 2050/4885 |
| US-20130259802-A1 | RADIOFLUORINATED COMPOUNDS AND THEIR PREPARATION | PSMA5, MPI, PSMA3 | SIGMAR1 1641/4885GFER 1938/4885MAOB 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.