⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028581 | 0.88 | CNR1 (0.34) | — | |
| SCHEMBL10000670 | 0.77 | — | — | |
| Water SCHEMBL31205630 | 0.67 | CNR1 (0.41) | — | |
| SCHEMBL10028580 | 0.65 | — | — | |
| SCHEMBL35560 | 0.65 | CNR1 (0.41) | — | |
| SCHEMBL35559 | 0.65 | CNR1 (0.41) | — | |
| SCHEMBL17732616 | 0.65 | CNR1 (0.41) | — | |
| SCHEMBL25119678 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL20846792 | 0.62 | CNR1 (0.40) | — | |
| SCHEMBL605200 | 0.62 | POLB (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119830-B2 | Dual function UV-absorbers for ophthalmic lens materials | NOVARTIS AG (CH) | 2012-02-21 | — | — | US | disclosed |
| US-20100168438-A1 | DUAL FUNCTION UV-ABSORBERS FOR OPHTHALMIC LENS MATERIALS | ALCON, INC. (CH) | 2010-07-01 | — | — | US | disclosed |
| US-7709652-B2 | Dual function UV-absorbers for ophthalmic lens materials | ALCON, INC. (CH) | 2010-05-04 | — | — | US | disclosed |
| US-20080221675-A1 | Dual Function UV-Absorbers for Ophthalmic Lens Materials | ALCON, INC. (CH) | 2008-09-11 | — | — | US | disclosed |
| US-7396942-B2 | Dual function UV-absorbers for ophthalmic lens materials | ALCON, INC. (CH) | 2008-07-08 | — | — | US | disclosed |
| US-20070078196-A1 | Dual Function UV-Absorbers for Ophthalmic Lens Materials | ALCON, INC. (US) | 2007-04-05 | — | — | US | disclosed |