Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158 | 1.00 | ESR2 (0.55) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL30503 | 0.85 | ESR2 (0.53) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL7767235 | 0.79 | ESR2 (0.40) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL7767231 | 0.79 | ESR2 (0.40) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL7767233 | 0.79 | ESR2 (0.40) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL10024807 | 0.79 | ESR2 (0.58) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL31104 | 0.79 | ESR2 (0.58) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL20749340 | 0.79 | ESR2 (0.46) | ESR2CYP2C9HDAC8HDAC6HDAC1 | |
| SCHEMBL11196166 | 0.77 | ESR2 (0.77) | ESR2CYP2C9ESR1CYP3A4NPC1 | |
| SCHEMBL8731134 | 0.76 | CYP2C9 (0.50) | ESR2CYP2C9ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |