Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158 | 0.85 | ESR2 (0.55) | ESR2CYP2C9HDAC8HDAC6ALDH1A1 | |
| SCHEMBL10000804 | 0.85 | ESR2 (0.55) | ESR2CYP2C9HDAC8HDAC6ALDH1A1 | |
| SCHEMBL10024807 | 0.77 | ESR2 (0.58) | ESR2CYP2C9HDAC8HDAC6ALDH1A1 | |
| SCHEMBL31104 | 0.77 | ESR2 (0.58) | ESR2CYP2C9HDAC8HDAC6ALDH1A1 | |
| SCHEMBL11196166 | 0.75 | ESR2 (0.77) | ESR2CYP2C9ESR1CYP3A4 | |
| SCHEMBL8725708 | 0.74 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8725713 | 0.74 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8725716 | 0.74 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8725709 | 0.74 | CYP2C9 (0.35) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL30854 | 0.73 | ESR2 (0.53) | ESR2CYP2C9HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| EP-2609172-B1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-07 | — | — | EP | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |