Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 3/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | HPGD | P15428 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60627 | 1.00 | RAB9A (0.77) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL13486845 | 0.93 | MAPT (0.69) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL13486843 | 0.93 | MAPT (0.69) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL1003538 | 0.89 | RAB9A (0.65) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL12056707 | 0.88 | NPC1 (1.00) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL18806558 | 0.88 | NPC1 (1.00) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL18806572 | 0.88 | NPC1 (1.00) | RAB9AMAPTNPC1MAPK1KDM4E | |
| SCHEMBL12307345 | 0.88 | NPC1 (1.00) | RAB9AMAPTNPC1MAPK1KDM4E | |
| Anthracene SCHEMBL9005940 | 0.86 | MAPT (0.61) | RAB9AMAPTNPC1MAPK1KDM4E | |
| Acetophenone SCHEMBL27096615 | 0.86 | RAB9A (0.67) | RAB9AMAPTNPC1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165227-A1 | COMPOUNDS AND METHODS FOR DETECTION AND QUANTIFICATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165227-A1 | COMPOUNDS AND METHODS FOR DETECTION AND QUANTIFICATION OF CARBOXYLIC ACIDS | AKR1C3, AR, AKR1C4 | RAB9A 1407/4885MAPT 4517/4885NPC1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.