SCHEMBL10001972

SCHEMBL10001972

Cc1ccc(C(C)(C(=O)O)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
KIF11 P52732 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
KMT2A Q03164 1/20 0.40
CYP19A1 P11511 1/20 0.40
MCL1 Q07820 1/20 0.39
ESR1 P03372 2/20 0.39
CYP2C9 P11712 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 3/20 0.38
ALDH1A1 P00352 2/20 0.38
FKBP5 Q13451 1/20 0.38
ESR2 Q92731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064266 0.87 CYP2D6 (0.37) CES2CES1CYP1A2CYP2D6KIF11
SCHEMBL31011016 0.83 ESR1 (0.61) TDP1ESR1ALDH1A1ESR2
SCHEMBL4204668 0.83 ESR1 (0.61) TDP1ESR1ALDH1A1ESR2
SCHEMBL30567643 0.83 ESR1 (0.61) TDP1ESR1ALDH1A1ESR2
SCHEMBL10228100 0.83 APP (0.47) CES2CES1CYP1A2CYP2D6KIF11
SCHEMBL27965746 0.77 ESR1 (0.64) TDP1RAB9AKMT2AESR1SMN1; SMN2
SCHEMBL16681051 0.77 TDP1 (0.43) CES2CES1CYP1A2CYP2D6KIF11
SCHEMBL15425832 0.76 CYP2C9 (0.45) CYP1A2CYP2D6NPC1KMT2AESR1
SCHEMBL27957395 0.76 TSHR (0.48) CES2CES1KIF11TDP1NPC1
SCHEMBL6671026 0.75 CES2 (0.40) CES2CES1CYP1A2CYP2D6KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8673540-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2014-03-18 US disclosed
US-20130095426-A1 PHOTOSENSITIVE POLYMIDES ETERNAL CHEMICAL CO., LTD. (TW) 2013-04-18 US disclosed
US-8349539-B2 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2013-01-08 US disclosed
US-8105752-B2 Photosensitive polyimides ETERNAL CHEMICAL CO., LTD. (TW) 2012-01-31 US disclosed
US-8105752-B2 Photosensitive polyimides ETERNAL CHEMICAL CO., LTD. (TW) 2012-01-31 US disclosed
US-20110212402-A1 PHOTOSENSITIVE RESIN COMPOSITION AND ITS APPLICATION ETERNAL CHEMICAL CO., LTD. (TW) 2011-09-01 US disclosed
US-20100086871-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2010-04-08 US disclosed
US-20100086874-A1 Photosensitive polymides ETERNAL CHEMICAL CO., LTD. (TW) 2010-04-08 US disclosed
US-20100086871-A1 PHOTOSENSITIVE POLYIMIDES ETERNAL CHEMICAL CO., LTD. 2010-04-08 US disclosed