Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.82 |
| ▸ | DAO | P14920 | 1/20 | 0.82 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.82 |
| ▸ | CES2 | O00748 | 3/20 | 0.67 |
| ▸ | CES1 | P23141 | 3/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL10528722 | 1.00 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10425703 | 0.97 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL10529216 | 0.95 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL975929 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL7719037 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 0.91 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546513-B2 | Catalytic polymerization of polymers containing electrophiic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-10-01 | — | — | US | claimed |
| US-20130123458-A1 | CATALYTIC POLYMERIZATION OF POLYMERS CONTAINING ELECTROPHIIC LINKAGES USING NUCLEOPHILIC REAGENTS | THE BOARD OF DIRECTORS OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-05-16 | — | — | US | claimed |
| US-8367796-B2 | Catalytic polymerization of polymers containing electrophilic linkages using nucleophilic reagents | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2013-02-05 | — | — | US | claimed |
| EP-3280537-B1 | CENTRIFUGE COUNTERBALANCE WITH ADJUSTABLE CENTER OF GRAVITY AND METHODS FOR USING THE SAME | ARTERIOCYTE MEDICAL SYSTEMS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| US-12038326-B2 | Methods for spectrally resolving fluorophores of a sample and systems for same | BECTON, DICKINSON AND COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| EP-3785015-B1 | FLOW CYTOMETERS HAVING ENCLOSED DROPLET SORTERS WITH CONTROLLED AEROSOL CONTENT AND METHODS OF USING THE SAME | BECTON DICKINSON CO (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2024129707-A1 | REAL-TIME ADAPTIVE METHODS FOR SPECTRALLY RESOLVING FLUOROPHORES OF A SAMPLE AND SYSTEMS FOR SAME | BECTON, DICKINSON AND COMPANY (US) | 2024-06-20 | — | — | WO | disclosed |
| US-20240192122-A1 | REAL-TIME ADAPTIVE METHODS FOR SPECTRALLY RESOLVING FLUOROPHORES OF A SAMPLE AND SYSTEMS FOR SAME | BECTON, DICKINSON AND COMPANY | 2024-06-13 | — | — | US | disclosed |
| US-11988589-B2 | Parameters for use in particle discrimination | BECTON, DICKINSON AND COMPANY (US) | 2024-05-21 | — | — | US | disclosed |
| US-11978269-B2 | Reconfigurable integrated circuits for adjusting cell sorting classification | BECTON, DICKINSON AND COMPANY (US) | 2024-05-07 | — | — | US | disclosed |
| US-11971343-B2 | Dual excitation beams for irradiating a sample in a flow stream and methods for using same | BECTON, DICKINSON AND COMPANY (US) | 2024-04-30 | — | — | US | disclosed |
| US-5773144-A | FIBERS, FILAMENTS USEFUL FOR RUBBER REINFORCEMENT, ESPECIALLY TIRES | HOECHST CELANESE CORP. (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1998008619-A1 | METHOD FOR MELT-COATING SURFACES WITH CURABLE POWDER POLYMER COMPOSITIONS | HOECHST CELANESE CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |
| US-5654097-A | POLYESTER, POLYAMIDE CORE, THERMOPLASTIC SHEATH; TIRE REINFORCEMENT | HOECHST CELANESE CORP. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5624754-A | MULTICOMPONENT FILAMENTS COMPRISING POLYESTER CORE AND A SHEATH OF A COMPATIBLE THERMOPLASTIC ELASTOMER BLENDS | HOECHST CELANESE CORP. (US) | 1997-04-29 | — | — | US | disclosed |
| US-5597651-A | Rubber-polyester composites including polystyrene-polyester copolymers | HOECHST CELANESE CORP. (US) | 1997-01-28 | — | — | US | disclosed |
| EP-0154985-A2 | Organosilicon/oxirane additives for filled condensation polymer composites | UNION CARBIDE CORPORATION (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4542174-A | NONHYDROLYZING, STORAGE STABLE | UNION CARBIDE CORPORATION (US) | 1985-09-17 | — | — | US | disclosed |
| US-3995091-A | Wire coated with a fluorocarbon polymer cross-linked with esters of sulfonyl dibenzoic acid | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3985716-A | POLYMER-CROSSLINKING CATALYST | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |