⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965616 | 0.82 | — | — | |
| SCHEMBL2023828 | 0.82 | — | — | |
| SCHEMBL14852728 | 0.72 | — | — | |
| SCHEMBL24383798 | 0.72 | — | — | |
| SCHEMBL8336163 | 0.72 | — | — | |
| SCHEMBL473764 | 0.67 | — | — | |
| SCHEMBL11592495 | 0.64 | — | — | |
| SCHEMBL2864265 | 0.64 | — | — | |
| SCHEMBL67200 | 0.64 | — | — | |
| SCHEMBL9051136 | 0.64 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3716956-B1 | ANTITUMOR TET2 MODULATING COMPOUNDS | CLEVELAND CLINIC FOUND (US) | 2024-06-26 | — | — | EP | disclosed |
| CN-117945844-A | Third monomer for EVA synthesis, modified EVA and application of modified EVA in EVOH synthesis | 中国科学院长春应用化学研究所 | 2024-04-30 | — | — | CN | disclosed |
| US-11760770-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| US-20210317143-A9 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-10-14 | — | — | US | disclosed |
| WO-2020236253-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |
| US-20200369685-A1 | BORONIC ESTER PRODRUGS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2020-11-26 | — | — | US | disclosed |
| EP-2863914-B1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME (US) | 2018-10-03 | — | — | EP | disclosed |
| US-9243004-B2 | Synthesis of boronic esters and boronic acids using grignard reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-26 | — | — | US | disclosed |
| US-9242984-B2 | Pyrazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150191461-A1 | PYRAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-07-09 | — | — | US | disclosed |
| US-5202386-A | Adhesion to polar material | AKZO NV (NL) | 1993-04-13 | — | — | US | disclosed |
| US-5037892-A | Epoxidation Of Olefin Polymers | AKZO N.V. (NL) | 1991-08-06 | — | — | US | disclosed |
| EP-0322945-A1 | Modification of (co)polymers employing organic peroxides | Akzo Nobel N.V. (NL) | 1989-07-05 | — | — | EP | disclosed |
| EP-0108627-A2 | Cephalosporin derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
| US-4226892-A | Flavoring with cycloaliphatic unsaturated ketones | FIRMENICH SA (CH) | 1980-10-07 | — | — | US | disclosed |
| US-4187863-A | Cycloaliphatic unsaturated ketones as odor and taste modifying agents in tobacco products | FIRMENICH SA (CH) | 1980-02-12 | — | — | US | disclosed |
| US-4048178-A | Novel N-allyl and N-propargyl benzmorphan derivatives | SMITH KLINE & FRENCH LABORATORIES (US) | 1977-09-13 | — | — | US | disclosed |
| US-3975310-A | PERFUME | FIRMENICH S.A. (CH) | 1976-08-17 | — | — | US | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
| US-3931326-A | FLAVOR, TASTE, ODOR, PERFUMES | FIRMENICH SA (CH) | 1976-01-06 | — | — | US | disclosed |