Phenylalanine

Phenylalanine

SCHEMBL1000408

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 7/20 0.65
ALPI P09923 1/20 0.65
PKM P14618 1/20 0.65
PTGS1 P23219 1/20 0.65
XIAP P98170 1/20 0.65
ANPEP P15144 2/20 0.58
RNPEP Q9H4A4 2/20 0.58
DNPEP Q9ULA0 2/20 0.58
SLC1A3 P43003 2/20 0.56
SLC1A2 P43004 2/20 0.56
SLC1A1 P43005 2/20 0.56
LTA4H P09960 1/20 0.54
NOS3 P29474 1/20 0.46
NOS1 P29475 1/20 0.46
NOS2 P35228 1/20 0.46
SLC15A1 P46059 1/20 0.45
GRIK1 P39086 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL1065019 1.00 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL3280667 0.97 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28432049 0.95 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1499939 0.95 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL26626971 0.95 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8595582 0.92 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL6237224 0.92 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL1679190 0.92 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL4283680 0.92 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL531086 0.92 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57134496-A None JP disclosed
CN-102665749-B Oral anti-inflammatory agent and oral anti-inflammatory peptide FUJI OIL CO LTD 2014-09-17 CN disclosed
CN-102665749-A Oral anti-inflammatory agent and oral anti-inflammatory peptide FUJI OIL CO LTD 2012-09-12 CN disclosed
US-20120157395-A1 ANTI-INFLAMMATORY AGENT FOR ORAL APPLICATION, AND ANTI-INFLAMMATORY PEPTIDE FOR ORAL APPLICATION YOSHINORI MINE (CA) 2012-06-21 US disclosed
US-20120157395-A1 ANTI-INFLAMMATORY AGENT FOR ORAL APPLICATION, AND ANTI-INFLAMMATORY PEPTIDE FOR ORAL APPLICATION YOSHINORI MINE (CA) 2012-06-21 US disclosed
WO-2011007612-A1 ANTI-INFLAMMATORY AGENT FOR ORAL APPLICATION, AND ANTI-INFLAMMATORY PEPTIDE FOR ORAL APPLICATION 不二製油株式会社 (JP) 2011-01-20 WO disclosed
US-7501397-B2 Helical peptidomimetics with enhanced activity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2009-03-10 US disclosed
EP-1572076-A3 HELICAL PEPTIDOMIMETICS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2005-12-21 EP disclosed
WO-2005118634-A2 HELICAL PEPTIDOMIMETICS WITH ENHANCED ACTIVITY AGAINST BETA-AMYLOID PRODUCTION THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2005-12-15 WO disclosed
US-20050272659-A1 Helical peptidomimetics with enhanced activity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2005-12-08 US disclosed
EP-1152769-A1 YEAST CELL WALL PEPTIDES AND ANTIBODIES THERETO THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2001-11-14 EP disclosed
WO-2001062958-A1 ASSESSMENT OF THE FUNCTIONAL SIGNIFICANCE OF A NUCLEOTIDE SEQUENCE BY SUBJECTING THE READING FRAME DATA TO DATA PROCESSING NATIONAL CANCER CENTRE OF SINGAPORE PTE LTD. (SG) 2001-08-30 WO disclosed
WO-2000048620-A1 YEAST CELL WALL PEPTIDES AND ANTIBODIES THERETO UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2000-08-24 WO disclosed
EP-0331821-B1 ANTIVIRAL AGENT KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
US-4663438-A ANTITUMOR AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-05-05 US disclosed
US-4663438-A ANTITUMOR AGENTS KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-05-05 US disclosed
EP-0058093-B1 GLYCOPROTEIN HAVING ANTI-TUMOUR AND LECTIN-LIKE ACTIVITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-10-24 EP disclosed
JP-S57134496-A NOVEL CONJUGATED GLYCOPROTEIN KUREHA CHEM IND CO LTD 1982-08-19 JP disclosed
EP-0058093-A1 Glycoprotein having anti-tumour and lectin-like activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-08-18 EP disclosed
EP-0058093-A1 Glycoprotein having anti-tumour and lectin-like activity KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-08-18 EP disclosed