Phenylalanine

Phenylalanine

SCHEMBL3280667

CC(C)C[C@H](N)C(=O)O.CC(C)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.61
ALPI P09923 1/20 0.61
PKM P14618 1/20 0.61
PTGS1 P23219 1/20 0.61
XIAP P98170 1/20 0.61
ANPEP P15144 2/20 0.56
RNPEP Q9H4A4 2/20 0.56
DNPEP Q9ULA0 2/20 0.56
SLC1A3 P43003 2/20 0.54
SLC1A2 P43004 2/20 0.54
SLC1A1 P43005 2/20 0.54
LTA4H P09960 1/20 0.52
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
SLC15A1 P46059 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL1065019 0.97 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1000408 0.97 SLC7A5 (0.65) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6274269 0.93 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8532962 0.93 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL6535452 0.93 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL26626971 0.92 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28432049 0.92 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL1499939 0.92 SLC7A5 (0.58) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8595582 0.90 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2634732 0.90 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7704987-B1 β-amyloid peptide inhibitors PRANA BIOTECHNOLOGY LTD (AU) 2010-04-27 US disclosed