Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20257559 | 0.89 | CHRM2 (0.43) | HTR2AHRH1HTR2CGAAHRH3 | |
| SCHEMBL18390906 | 0.82 | SIGMAR1 (0.43) | HRH1GAAHRH3HRH4PRKCG | |
| SCHEMBL3360174 | 0.81 | HRH3 (0.42) | HTR2AHRH1HTR2CHRH3HRH4 | |
| SCHEMBL1372038 | 0.80 | SIGMAR1 (0.47) | HRH1GAAHRH3PRKCGPRKCB | |
| SCHEMBL3359924 | 0.78 | CHKA (0.41) | HTR2AHRH1HTR2CHRH3HRH4 | |
| SCHEMBL23011824 | 0.78 | HTR2A (0.34) | HTR2AHRH1HTR2CGAAHRH3 | |
| SCHEMBL303012 | 0.76 | HTR2A (0.33) | HTR2AHRH1HTR2CGAAHRH3 | |
| SCHEMBL21049518 | 0.75 | HRH3 (0.34) | HTR2AHRH1HTR2CGAAHRH3 | |
| SCHEMBL301474 | 0.74 | HTR2A (0.37) | HTR2AHRH1HTR2CGAAHRH3 | |
| SCHEMBL18202061 | 0.74 | HRH3 (0.34) | HTR2AHRH1HTR2CGAAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120006229-A1 | AQUEOUS SOLUTION OF PIPERAZINYL-CONTAINING SILANOL COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |