Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 3/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | KDM1A | O60341 | 2/20 | 0.57 |
| ▸ | EP300 | Q09472 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 7/20 | 0.55 |
| ▸ | NPY4R | P50391 | 7/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.55 |
| ▸ | NPY1R | P25929 | 5/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.55 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 1/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005991 | 0.90 | KISS1R (0.58) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005969 | 0.88 | NPY4R (0.59) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005999 | 0.88 | NPY4R (0.59) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10006003 | 0.88 | NPY4R (0.59) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005986 | 0.88 | NPY4R (0.59) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005993 | 0.87 | NPY4R (0.58) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10006027 | 0.87 | NPY4R (0.58) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005978 | 0.86 | NPY4R (0.57) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10006025 | 0.86 | NPY4R (0.57) | KISS1RNPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL10005998 | 0.86 | TFPI (0.57) | KISS1RNPY2RNPY4RNPY5RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450374-B9 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-9260500-B2 | Peptide and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-02-16 | — | — | US | disclosed |
| EP-2450374-B1 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2015-09-30 | — | — | EP | disclosed |
| US-20120172293-A1 | PEPTIDE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172293-A1 | PEPTIDE AND USE THEREOF | GLP1R, GIPR, SCTR | KISS1R 88/4885MAPK8 1608/4885MAPK9 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.