Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | SLC5A2 | P31639 | 13/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15532111 | 1.00 | KDM4E (0.53) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8368995 | 1.00 | KDM4E (0.53) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8134982 | 0.90 | KDM4E (0.45) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8367682 | 0.88 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8371823 | 0.88 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6008963 | 0.88 | KDM4E (0.55) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8175230 | 0.86 | KDM4E (0.53) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8370794 | 0.83 | KDM4E (0.50) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL1030161 | 0.81 | KDM4E (0.48) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8367465 | 0.81 | KDM4E (0.48) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768273-A1 | METHODS AND SYNERGIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS | Hadasit Medical Research Services and Development Ltd. (IL) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019180708-A1 | METHODS AND SYNERGIC COMPOSITIONS FOR TREATING VIRAL INFECTIONS | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2019-09-26 | — | — | WO | disclosed |
| WO-2015038639-A1 | THERAPEUTIC ASPARAGINASES | SANDIA CORPORATION (US) | 2015-03-19 | — | — | WO | disclosed |
| EP-2276479-A2 | PRODRUGS OF NEURAMINIDASE INHIBITORS | TSRL, Inc. (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2274042-A1 | TREATMENT AND/OR PREVENTION OF MULTIPLE SCLEROSIS | Epiphany Biosciences, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009129305-A2 | PRODRUGS OF NEURAMINIDASE INHIBITORS | TSRL, INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| WO-2009126327-A1 | TREATMENT AND/OR PREVENTION OF MULTIPLE SCLEROSIS | EPIPHANY BIOSCIENCES, INC. (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2006110728-A2 | IMMUNOGENIC CMV TEGUMENT AGGREGATES | THE UAB RESEARCH FOUNDATION (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-1999051619-A1 | ARABINOFURANOSYL BENZIMIDAZOLES AS ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-10-14 | — | — | WO | disclosed |