Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298043 | 0.94 | HSD17B3 (0.43) | HSD17B3APEX1S1PR5HTR7MMP2 | |
| SCHEMBL10009406 | 0.87 | HSD17B3 (0.39) | HSD17B3APEX1S1PR5STS | |
| SCHEMBL10010050 | 0.85 | HSD17B3 (0.43) | HSD17B3STS | |
| SCHEMBL28228004 | 0.83 | HSD17B3 (0.47) | HSD17B3APEX1STS | |
| SCHEMBL10008935 | 0.83 | HSD17B3 (0.44) | HSD17B3S1PR5HTR7MMP2MMP12 | |
| SCHEMBL28228075 | 0.83 | HSD17B3 (0.47) | HSD17B3APEX1STS | |
| SCHEMBL18812919 | 0.82 | APEX1 (0.54) | APEX1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18012830 | 0.81 | HSD17B3 (0.50) | HSD17B3S1PR5HTR7PTGS2STS | |
| SCHEMBL27761329 | 0.79 | RARB (0.47) | — | |
| SCHEMBL10298042 | 0.78 | HSD17B3 (0.37) | HSD17B3PTGS2STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8854730-B2 | Negatively birefringent polyesters and optical films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | PUF60, PARG, PARN | HSD17B3 3615/4885APEX1 997/4885S1PR5 2366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.