Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.43 |
| ▸ | HRH2 | P25021 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298042 | 0.92 | HSD17B3 (0.37) | HSD17B3HRH2HRH1NR4A1PDK2 | |
| SCHEMBL10009406 | 0.88 | HSD17B3 (0.39) | HSD17B3HRH2HRH1NR4A1STS | |
| SCHEMBL10008412 | 0.85 | HSD17B3 (0.48) | HSD17B3STS | |
| SCHEMBL10298043 | 0.82 | HSD17B3 (0.43) | HSD17B3L3MBTL1 | |
| SCHEMBL28228075 | 0.79 | HSD17B3 (0.47) | HSD17B3PDK2ALDH1A1STSL3MBTL1 | |
| SCHEMBL28228004 | 0.79 | HSD17B3 (0.47) | HSD17B3PDK2ALDH1A1STSL3MBTL1 | |
| SCHEMBL10008935 | 0.79 | HSD17B3 (0.44) | HSD17B3STS | |
| SCHEMBL18012830 | 0.77 | HSD17B3 (0.50) | HSD17B3ALDH1A1STS | |
| SCHEMBL13814976 | 0.77 | PDK2 (0.40) | PDK2ALDH1A1 | |
| SCHEMBL17050249 | 0.74 | APEX1 (0.51) | PDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8854730-B2 | Negatively birefringent polyesters and optical films | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | 3M INNOVATIVE PROPERTIES COMPANY | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170118-A1 | NEGATIVELY BIREFRINGENT POLYESTERS AND OPTICAL FILMS | PUF60, PARG, PARN | HSD17B3 3615/4885HRH2 4866/4885HRH1 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.