Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29470540 | 1.00 | KMT2A (0.45) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL1745934 | 1.00 | KMT2A (0.45) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL31146900 | 1.00 | KMT2A (0.45) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL3367289 | 1.00 | KMT2A (0.45) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL29368397 | 1.00 | KMT2A (0.45) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL14416300 | 0.93 | KMT2A (0.42) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL13183250 | 0.92 | KMT2A (0.42) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL30558303 | 0.92 | KMT2A (0.42) | KMT2AMEN1CASP3NPC1RAB9A | |
| SCHEMBL12873284 | 0.92 | LMNA (0.46) | KMT2AMEN1CASP3MDM2FABP5 | |
| SCHEMBL12555211 | 0.92 | KMT2A (0.47) | KMT2AMEN1CASP3MDM2FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014144383-A1 | NON-COVALENT PATTERNED CHEMICAL FEATURES AND USE THEREOF IN MALDI-BASED QUALITY CONTROL | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2014-09-18 | — | — | WO | claimed |
| EP-0929567-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | Zealand Pharmaceuticals A/S (DK) | 1999-07-21 | — | — | EP | claimed |
| US-5858534-A | FOR SOLID PHASE SYNTHESIS; POLYSTYRENE COATED METAL OXIDE PARTICLES DISPERSED IN POLYSTYRENE MATRIX | SOLID PHASE SCIENCES CORP. (US) | 1999-01-12 | — | — | US | claimed |
| WO-1998011125-A1 | IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS | ZEALAND PHARMACEUTICALS A/S (DK) | 1998-03-19 | — | — | WO | claimed |
| US-20180362611-A1 | PEPTIDE AGONISTS OF GLP-1 ACTIVITY | ZEALAND PHARMACEUTICALS A/S (DK) | 2018-12-20 | — | — | US | disclosed |
| EP-2272866-B1 | THERAPEUTICALLY ACTIVE ALPHA-MSH ANALOGUES | ABBVIE INC (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20170313740-A1 | METHODS OF PREPARING PEPTIDES | C S Bio Co. | 2017-11-02 | — | — | US | disclosed |
| WO-2017189925-A1 | METHODS OF PREPARING PEPTIDES | C S Bio Co. (US) | 2017-11-02 | — | — | WO | disclosed |
| US-20170107267-A1 | PEPTIDE AGONISTS OF GLP-1 ACTIVITY | ZEALAND PHARMA A/S (DK) | 2017-04-20 | — | — | US | disclosed |
| US-9593155-B2 | Oxyntomodulin analogs | MERCK SHARP & DOHME CORP. (US) | 2017-03-14 | — | — | US | disclosed |
| EP-1991574-B1 | OXYNTOMODULIN DERIVATIVES | MERCK SHARP & DOHME (US) | 2016-10-12 | — | — | EP | disclosed |
| US-9382288-B2 | Derivatives of steroid benzylamines, having an antiparasitic antibacterial, antimycotic and/or antiviral action | JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) | 2016-07-05 | — | — | US | disclosed |
| EP-1085943-A1 | THREE-DIMENSIONAL ARRAY OF SUPPORTS FOR SOLID-PHASE PARALLEL SYNTHESIS AND METHOD OF USE | SELECTIDE CORPORATION (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1076066-A1 | Peptides for lowering blood glucose levels | Zealand Pharmaceuticals A/S (DK) | 2001-02-14 | — | — | EP | disclosed |
| EP-1062229-A1 | PHARMACOLOGICALLY ACTIVE PEPTIDE CONJUGATES HAVING A REDUCED TENDENCY TOWARDS ENZYMATIC HYDROLYSIS | Zealand Pharmaceuticals A/S (DK) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999059722-A1 | THREE-DIMENSIONAL ARRAY OF SUPPORTS FOR SOLID-PHASE PARALLEL SYNTHESIS AND METHOD OF USE | SELECTIDE CORPORATION (US) | 1999-11-25 | — | — | WO | disclosed |
| WO-1999046283-A9 | PHARMACOLOGICALLY ACTIVE PEPTIDE CONJUGATES HAVING A REDUCED TENDENCY TOWARDS ENZYMATIC HYDROLYSIS | ZEALAND PHARMACEUTICALS A S (DK) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999046283-A1 | PHARMACOLOGICALLY ACTIVE PEPTIDE CONJUGATES HAVING A REDUCED TENDENCY TOWARDS ENZYMATIC HYDROLYSIS | ZEALAND PHARMACEUTICALS A/S (DK) | 1999-09-16 | — | — | WO | disclosed |
| US-5858534-A | FOR SOLID PHASE SYNTHESIS; POLYSTYRENE COATED METAL OXIDE PARTICLES DISPERSED IN POLYSTYRENE MATRIX | SOLID PHASE SCIENCES CORP. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0714907-A1 | Oligoribonucleotides with amide backbone | F. HOFFMANN-LA ROCHE AG (CH) | 1996-06-05 | — | — | EP | disclosed |