SCHEMBL10011508

SCHEMBL10011508

Cc1cccc(-c2nnc(S)n2N=Cc2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.54
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 3/20 0.50
CYP2C9 P11712 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP3A4 P08684 1/20 0.50
ATM Q13315 1/20 0.50
MAPT P10636 5/20 0.46
HPGD P15428 5/20 0.46
POLB P06746 1/20 0.46
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 3/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
CYP2C19 P33261 1/20 0.43
GAA P10253 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10011505 1.00 CYP1A2 (0.54) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012422 0.89 MEN1 (0.56) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012421 0.89 MEN1 (0.56) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012601 0.87 MAPT (0.46) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012599 0.87 MAPT (0.46) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012630 0.86 POLB (0.49) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012633 0.86 POLB (0.49) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012881 0.86 MEN1 (0.54) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012883 0.86 MEN1 (0.54) CYP1A2KMT2AMEN1ALDH1A1CYP2C9
SCHEMBL10012408 0.83 LMNA (0.46) CYP1A2KMT2AMEN1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753895-B2 Surface modified metal nano-particle and use thereof Postech Academy-Industries Foundation (KR) 2014-06-17 US disclosed
US-20130252274-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-09-26 US disclosed
US-20120168681-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-07-05 US disclosed