SCHEMBL10011646

SCHEMBL10011646

CCCCC/C=C\C/C=C\CCCCCCC(CC(O)CO)(CC(O)CO)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.52
ALDH1A1 P00352 5/20 0.50
PPARG P37231 5/20 0.50
F7 P08709 4/20 0.50
F3 P13726 4/20 0.50
PPARD Q03181 4/20 0.50
PPARA Q07869 4/20 0.50
FFAR1 O14842 3/20 0.50
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
CYP3A4 P08684 2/20 0.50
CYP19A1 P11511 2/20 0.50
FABP4 P15090 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
PTGS1 P23219 2/20 0.50
AKR1C3 P42330 2/20 0.50
NR4A2 P43354 2/20 0.50
HSD17B10 Q99714 2/20 0.50
TDP1 Q9NUW8 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29288574 0.96 DGKA (0.51) FAAHPPARGF7F3PPARD
SCHEMBL74732 0.96 DGKA (0.51) FAAHPPARGF7F3PPARD
SCHEMBL1854340 0.96 DGKA (0.51) FAAHPPARGF7F3PPARD
SCHEMBL17091428 0.93 DGKA (0.51) FAAHPPARGF7F3PPARD
SCHEMBL3036962 0.93 DGKA (0.51) FAAHPPARGF7F3PPARD
SCHEMBL18952108 0.91 PPARG (0.62) FAAHALDH1A1PPARGF7F3
SCHEMBL18952122 0.91 PPARG (0.62) FAAHALDH1A1PPARGF7F3
SCHEMBL18952065 0.89 PPARG (0.59) FAAHALDH1A1PPARGF7F3
SCHEMBL18952055 0.89 PPARG (0.59) FAAHALDH1A1PPARGF7F3
SCHEMBL4442370 0.87 FFAR1 (0.61) FAAHALDH1A1PPARGF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658610-B1 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE BLUME GABRIELE (DE) 2016-05-04 EP claimed
US-9161921-B2 Colloidal carrier system with penetration properties for encapsulating lipophilic active agents and oils for topical use BLUME GABRIELE (DE) 2015-10-20 US claimed
US-20130273123-A1 Colloidal Carrier System with Penetration Properties for Encapsulating Lipophilic Active Agents and Oils for Topical Use BLUME GABRIELE (DE) 2013-10-17 US claimed
EP-2658610-B1 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE BLUME GABRIELE (DE) 2016-05-04 EP disclosed
US-9161921-B2 Colloidal carrier system with penetration properties for encapsulating lipophilic active agents and oils for topical use BLUME GABRIELE (DE) 2015-10-20 US disclosed
US-9161921-B2 Colloidal carrier system with penetration properties for encapsulating lipophilic active agents and oils for topical use BLUME GABRIELE (DE) 2015-10-20 US disclosed
EP-2658610-A2 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE Blume, Gabriele (DE) 2013-11-06 EP disclosed
EP-2658610-A2 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE Blume, Gabriele (DE) 2013-11-06 EP disclosed
US-20130273123-A1 Colloidal Carrier System with Penetration Properties for Encapsulating Lipophilic Active Agents and Oils for Topical Use BLUME GABRIELE (DE) 2013-10-17 US disclosed
US-20130273123-A1 Colloidal Carrier System with Penetration Properties for Encapsulating Lipophilic Active Agents and Oils for Topical Use BLUME GABRIELE (DE) 2013-10-17 US disclosed
WO-2012089184-A3 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE BLUME GABRIELE (DE) 2013-07-04 WO disclosed
WO-2012089184-A2 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE BLUME GABRIELE (DE) 2012-07-05 WO disclosed
WO-2012089184-A2 COLLOIDAL CARRIER SYSTEM WITH PENETRATION PROPERTIES FOR ENCAPSULATING LIPOPHILIC ACTIVE AGENTS AND OILS FOR TOPICAL USE BLUME GABRIELE (DE) 2012-07-05 WO disclosed