SCHEMBL1001229

SCHEMBL1001229

CC([O])OS(C)(=O)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL575530 0.76 ALDH1A1 (0.65)
SCHEMBL1822384 0.76 ALDH1A1 (0.65)
SCHEMBL331716 0.76
SCHEMBL5553793 0.76 ALDH1A1 (0.65)
SCHEMBL5830076 0.76 ALDH1A1 (0.65)
SCHEMBL8474324 0.75 ALDH1A1 (0.55)
SCHEMBL11155362 0.75 ALDH1A1 (0.48)
SCHEMBL28088753 0.73
SCHEMBL14777975 0.71 ALDH1A1 (0.57)
SCHEMBL4596643 0.71 ALDH1A1 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5422367-A A hormon inhibitors and for inhibiting the development of an estrogen-dependent tumor RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-06-06 US claimed
US-20140309424-A1 DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F] FLUOROMETHYL) TYROSINE PIRAMAL IMAGING SA (CH) 2014-10-16 US disclosed
EP-2751087-A1 DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL)TYROSINE Piramal Imaging SA (CH) 2014-07-09 EP disclosed
WO-2013001088-A1 DIRECT SYNTHESIS OF 18F-FLUOROMETHOXY COMPOUNDS FOR PET IMAGING AND THE PROVISION OF NEW PRECURSORS FOR DIRECT RADIOSYNTHESIS OF PROTECTED DERIVATIVES OF O-([18F]FLUOROMETHYL) TYROSINE PIRAMAL IMAGING SA (CH) 2013-01-03 WO disclosed
US-7863465-B2 Antifungal agents MERCK SHARP & DOHME CORP. (US) 2011-01-04 US disclosed
EP-2007396-A1 ANTIFUNGAL AGENTS Merck and Co., Inc. (US) 2008-12-31 EP disclosed
US-20080009504-A1 Antifungal agents SCYNEXIS, INC. 2008-01-10 US disclosed
WO-2007127012-A1 ANTIFUNGAL AGENTS MERCK & CO., INC. (US) 2007-11-08 WO disclosed
EP-1137632-B1 THIOUREA INHIBITORS OF HERPES VIRUSES WYETH CORP (US) 2004-07-28 EP disclosed
EP-1137645-B1 ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP WYETH CORP (US) 2004-05-26 EP disclosed
WO-2000034261-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034268-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034238-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
WO-2000034260-A2 ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
US-5519139-A FUNGICIDES, INSTECTICIDES, MITICIDES SHIONOGI & CO., LTD. (JP) 1996-05-21 US disclosed
US-5439911-A A potent fungicides, insecticides and miticides SHIONOGI & CO., LTD. (JP) 1995-08-08 US disclosed
US-5422367-A A hormon inhibitors and for inhibiting the development of an estrogen-dependent tumor RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-06-06 US disclosed
EP-0606011-A1 Aminopyrimidine derivatives and their production and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI &amp; CO. LTD. (JP) 1994-07-13 EP disclosed
US-5324736-A Diphenylcyclopropyl analogs as antiestrogenic and antitumor agents RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-06-28 US disclosed
US-5098903-A Halocyclopropanes BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 1992-03-24 US disclosed