Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768577 | 0.80 | NQO2 (0.46) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL20931281 | 0.80 | ELANE (0.49) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30698496 | 0.79 | ALDH1A1 (0.51) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL27037459 | 0.79 | ALDH1A1 (0.51) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL5036483 | 0.79 | MCHR1 (0.50) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL6612807 | 0.78 | F2RL3 (0.42) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL31213014 | 0.77 | NQO2 (0.43) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL28056277 | 0.77 | ALDH1A1 (0.42) | NQO2ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL29098687 | 0.77 | KDM4E (0.52) | ALDH1A1KDM4EHPGDMEN1CYP1A2 | |
| SCHEMBL3117868 | 0.76 | F2RL3 (0.48) | NQO2ALDH1A1KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421222-B2 | Substituted quinazolines as HDAC6 inhibitors | AUGUSTINE THERAPEUTICS (BE) | 2025-09-23 | — | — | US | disclosed |
| US-20250145604-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-05-08 | — | — | US | disclosed |
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2025-02-13 | — | — | US | disclosed |
| WO-2023118507-A2 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | AUGUSTINE THERAPEUTICS (BE) | 2023-06-29 | — | — | WO | disclosed |
| US-8753895-B2 | Surface modified metal nano-particle and use thereof | Postech Academy-Industries Foundation (KR) | 2014-06-17 | — | — | US | disclosed |
| US-20130252274-A1 | Surface Modified Metal Nano-Particle and Use Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2013-09-26 | — | — | US | disclosed |
| US-20120168681-A1 | Surface Modified Metal Nano-Particle and Use Thereof | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051319-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | HDAC6, HDAC9, HDAC1 | NQO2 317/4885ALDH1A1 608/4885KDM4E 2750/4885 |
| US-20250145604-A1 | COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS | HDAC6, HDAC9, HDAC1 | NQO2 317/4885ALDH1A1 608/4885KDM4E 2750/4885 |
| US-12421222-B2 | Substituted quinazolines as HDAC6 inhibitors | HDAC6, HDAC9, HDAC1 | NQO2 69/4885ALDH1A1 850/4885KDM4E 3008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.