SCHEMBL10013048

SCHEMBL10013048

Sc1nnc(COc2ccc(Cl)cc2Cl)o1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 7/20 0.58
NPC1 O15118 7/20 0.58
RAB9A P51151 7/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
TSHR P16473 5/20 0.58
ALDH1A1 P00352 4/20 0.58
NPSR1 Q6W5P4 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
MAPT P10636 2/20 0.58
TP53 P04637 2/20 0.51
LMNA P02545 1/20 0.48
NFKB1 P19838 1/20 0.48
CASP3 P42574 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
GLA P06280 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570546 0.86 NPC1 (0.64) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL28578447 0.82 SMN1; SMN2 (0.65) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL31522220 0.80 HPGD (0.38) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL11351642 0.79 HPGD (0.60) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL10898999 0.78 TDP1 (0.55) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL31522242 0.77 TDP1 (0.60) NPC1RAB9ASMN1; SMN2TSHRALDH1A1
SCHEMBL31522219 0.75 TDP1 (0.42) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL24793360 0.73 HPGD (0.55) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL30745399 0.73 HPGD (0.55) HPGDNPC1RAB9ASMN1; SMN2TSHR
SCHEMBL11353689 0.71 ALDH1A1 (0.68) HPGDNPC1RAB9ASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930535-A 1,3, 4-Oxadiazole derivative containing biphenyl unit, and preparation method and application thereof 江苏海洋大学 2025-05-06 CN disclosed
CN-112898222-B Oxadiazole compound and preparation method and application thereof 长沙理工大学 2022-09-13 CN disclosed
CN-112898222-A Oxadiazole compound and preparation method and application thereof 长沙理工大学 2021-06-04 CN disclosed
US-8753895-B2 Surface modified metal nano-particle and use thereof Postech Academy-Industries Foundation (KR) 2014-06-17 US disclosed
US-20130252274-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-09-26 US disclosed
US-20120168681-A1 Surface Modified Metal Nano-Particle and Use Thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2012-07-05 US disclosed