SCHEMBL10013302

SCHEMBL10013302

C=C(C)C(=O)Oc1ccc(Oc2c(C)cc(C(C)(C)O)cc2C)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
ATM Q13315 1/20 0.45
ELANE P08246 2/20 0.44
LMNA P02545 1/20 0.33
THRA P10827 3/20 0.32
THRB P10828 3/20 0.32
AR P10275 1/20 0.32
MAPT P10636 2/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
ESRRA P11474 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ACHE P22303 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013301 0.88 KMT2A (0.44) KMT2AATMELANELMNATHRA
SCHEMBL19959100 0.85 KMT2A (0.49) KMT2AATMELANELMNATHRA
SCHEMBL10013315 0.83 KMT2A (0.40) KMT2AATMELANEAR
SCHEMBL10013319 0.82 ELANE (0.52) KMT2AATMELANELMNATHRA
SCHEMBL10013312 0.81 ELANE (0.54) KMT2AATMELANELMNAAR
SCHEMBL10013305 0.81 KMT2A (0.45) KMT2AATMELANETHRATHRB
SCHEMBL10013314 0.81 ELANE (0.48) KMT2AATMELANELMNATHRA
SCHEMBL10013313 0.80 KMT2A (0.38) KMT2AATMELANETHRATHRB
SCHEMBL17879997 0.80 ATM (0.36) KMT2AATMELANETHRATHRB
SCHEMBL21580265 0.79 ELANE (0.42) KMT2AATMELANEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180077796-A1 RESIN COMPOSITION ELIMINATING VOLATILE LOSS OF INITIATING SPECIES FOR THE PREPARATION OF PRINTED CIRCUIT BOARD LAMINATES INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-03-15 US disclosed
US-9888570-B2 Resin composition eliminating volatile loss of initiating species for the preparation of printed circuit board laminates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-02-06 US disclosed
US-20140343232-A1 RESIN COMPOSITION ELIMINATING VOLATILE LOSS OF INITIATING SPECIES FOR THE PREPARATION OF PRINTED CIRCUIT BOARD LAMINATES INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-11-20 US disclosed
US-20120045955-A1 Resin Composition Eliminating Volatile Loss of Initiating Species for the Preparation of Printed Circuit Board Laminates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-02-23 US disclosed