Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158096 | 0.96 | HDAC4 (0.52) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| Boric Acid SCHEMBL31280193 | 0.89 | HDAC4 (0.51) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL14195551 | 0.88 | HDAC4 (0.48) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL10013485 | 0.86 | SMN1; SMN2 (0.46) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL14555283 | 0.84 | HDAC4 (0.48) | HDAC4NPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL890214 | 0.83 | SMN1; SMN2 (0.47) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL14195545 | 0.82 | HDAC4 (0.43) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL18725088 | 0.82 | HDAC4 (0.44) | HDAC4CYP11B1CYP11B2NPC1RAB9A | |
| SCHEMBL11691090 | 0.81 | HSD17B1 (0.49) | HDAC4NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL2090445 | 0.80 | APP (0.44) | HDAC4NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |