Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013483 | 0.93 | HSD17B1 (0.42) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013476 | 0.92 | HSD17B1 (0.51) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013480 | 0.90 | HSD17B1 (0.44) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013453 | 0.90 | HSD17B1 (0.53) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL13142447 | 0.87 | HSD17B1 (0.49) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013447 | 0.87 | HSD17B1 (0.56) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013477 | 0.86 | HSD17B1 (0.56) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL13142442 | 0.85 | HSD17B1 (0.50) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL10013452 | 0.84 | HSD17B1 (0.58) | HSD17B1HSD17B2NPC1RAB9AKDM4E | |
| SCHEMBL13142461 | 0.83 | HSD17B1 (0.47) | HSD17B1HSD17B2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |
| US-8148543-B2 | A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current | CANON KABUSHIKI KAISHA (JP) | 2012-04-03 | — | — | US | disclosed |