SCHEMBL10014271

SCHEMBL10014271

Cc1ccc(OCC2CCC(C3CCC(C)CC3)CC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
PARP15 Q460N3 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP2 Q9UGN5 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
KDM1A O60341 2/20 0.43
DGAT1 O75907 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
MAOB P27338 1/20 0.40
AKT1 P31749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14451132 0.95 HPGD (0.52) HPGDPARP15PARP10PARP2TDP1
SCHEMBL14570008 0.90 KDM1A (0.49) HPGDPARP15PARP10PARP2TDP1
SCHEMBL13135282 0.88 HPGD (0.57) HPGDPARP15PARP10PARP2TDP1
SCHEMBL8930160 0.88 PARP15 (0.55) PARP15PARP10PARP2TDP1KDM1A
SCHEMBL2665020 0.88 PARP15 (0.55) PARP15PARP10PARP2TDP1KDM1A
SCHEMBL15181005 0.87 TDP1 (0.59) HPGDPARP15PARP10PARP2TDP1
Ammonia Solution, Strong SCHEMBL28413630 0.86 PARP15 (0.53) PARP15PARP10PARP2TDP1KDM1A
SCHEMBL18867116 0.85 PARP15 (0.44) PARP15PARP10PARP2TDP1KDM1A
SCHEMBL10091211 0.85 CARM1 (0.49) HPGDPARP15PARP10PARP2TDP1
SCHEMBL13111382 0.84 HPGD (0.47) HPGDPARP15PARP10PARP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10883047-B2 Liquid-crystalline medium and liquid-crystal display comprising the same MERCK PATENT GMBH (DE) 2021-01-05 US disclosed
US-20180086980-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-03-29 US disclosed
US-20180086980-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-03-29 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-9914878-B2 Composite liquid crystal composition, display element and electric field detector DIC CORPORATION (JP) 2018-03-13 US disclosed
US-9650573-B2 Liquid crystalline medium and liquid crystal device MERCK PATENT GMBH (DE) 2017-05-16 US disclosed
US-20170045765-A1 LCD DEVICE DIC CORPORATION (JP) 2017-02-16 US disclosed
US-20160319192-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT INCLUDING THE SAME DIC CORPORATION (JP) 2016-11-03 US disclosed
US-20160298035-A1 COMPOSITE LIQUID CRYSTAL COMPOSITION, DISPLAY ELEMENT AND ELECTRIC FIELD DETECTOR DIC CORPORATION (JP) 2016-10-13 US disclosed
US-20160122644-A1 METHOD OF UNIFORMIZING OUTPUT LIGHT OF LIQUID CRYSTAL DISPLAY ELEMENT AND LIQUID CRYSTAL DISPLAY ELEMENT TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2016-05-05 US disclosed
US-7604851-B2 Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2009-10-20 US disclosed
US-20080121843-A1 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices HECKMEIER MICHAEL 2008-05-29 US disclosed
US-7361388-B2 Liquid-crystalline compounds having a tetrahydropyran ring MERCK PATENT GMBH (DE) 2008-04-22 US disclosed
US-7361288-B2 Components for high-frequency technology MERCK PATENT GESELLSCHAFT MIT BESSCHRANKTER HAFTUNG (DE) 2008-04-22 US disclosed
US-7344761-B2 Liquid-crystalline compounds MERCK PATENT GESELLASCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-03-18 US disclosed
US-7303791-B2 Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices MERCK PATENT GMBH (DE) 2007-12-04 US disclosed
US-20070269614-A1 Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys HECKMEIER MICHAEL 2007-11-22 US disclosed
US-7291367-B2 Liquid-crystalline compounds MERCK PATENT GMBH (DE) 2007-11-06 US disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed