SCHEMBL10014286

SCHEMBL10014286

CC(=O)NCC1(C)CC(NC(C)=O)CC(C)(C)C1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.64
OPRM1 P35372 1/20 0.38
OPRL1 P41146 1/20 0.38
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
ATM Q13315 1/20 0.32
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10203832 0.91 TSHR (0.61) TSHROPRM1OPRL1ALDH1A1TDP1
SCHEMBL21010251 0.89 TSHR (0.59) TSHROPRM1OPRL1ALDH1A1TDP1
SCHEMBL20445661 0.89 TSHR (0.59) TSHROPRM1OPRL1TDP1
SCHEMBL12745269 0.88 TSHR (0.58) TSHROPRM1OPRL1ALDH1A1TDP1
SCHEMBL18019580 0.88 TSHR (0.58) TSHROPRM1OPRL1TDP1ALOX15
SCHEMBL10044232 0.88 TSHR (0.84) TSHROPRM1OPRL1ALDH1A1TDP1
SCHEMBL26080275 0.88 TSHR (0.58) TSHROPRM1OPRL1TDP1GAA
SCHEMBL14379799 0.88 TSHR (0.58) TSHROPRM1OPRL1ALDH1A1TDP1
SCHEMBL16684434 0.88 TSHR (0.84) TSHRTDP1
SCHEMBL23019939 0.87 TSHR (0.56) TSHROPRM1OPRL1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134280-A1 CATALYSTS FOR THE FORMATION OF POLYURETHANES MOMENTIVE PERFORMANCE MATERIALS INC. 2023-05-04 US disclosed
EP-2653511-B1 Active energy ray-curable ink composition, inkjet recording method, and method for producing in-molded product FUJIFILM CORP (JP) 2019-07-31 EP disclosed
EP-2949710-B1 RADIATION-CURABLE INK COMPOSITION, INK SET, INKJET RECORDING METHOD, DECORATIVE SHEET, DECORATIVE SHEET MOLDED PRODUCT, PROCESS FOR PRODUCING IN-MOLD MOLDED ARTICLE, AND IN-MOLD MOLDED ARTICLE FUJIFILM CORP (JP) 2019-05-15 EP disclosed
EP-3053974-B1 PIGMENT DISPERSION COMPOSITION, INKJET RECORDING METHOD, AND METHOD FOR PRODUCING COMPOUND FUJIFILM CORP (JP) 2017-10-25 EP disclosed
US-9737607-B2 Polymer, and pharmaceutical composition employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-08-22 US disclosed
US-9643404-B2 Pigment dispersion composition, inkjet recording method, and method for producing compound FUJIFILM CORPORATION (JP) 2017-05-09 US disclosed
US-9643404-B2 Pigment dispersion composition, inkjet recording method, and method for producing compound FUJIFILM CORPORATION (JP) 2017-05-09 US disclosed
US-9464160-B2 Fluorinated ethoxylated polyurethanes THE CHEMOURS COMPANY FC, LLC (US) 2016-10-11 US disclosed
EP-3053974-A1 PIGMENT DISPERSION COMPOSITION, INKJET RECORDING METHOD, AND METHOD FOR PRODUCING COMPOUND FUJIFILM Corporation (JP) 2016-08-10 EP disclosed
US-20160200926-A1 PIGMENT DISPERSION COMPOSITION, INKJET RECORDING METHOD, AND METHOD FOR PRODUCING COMPOUND FUJIFILM CORPORATION (JP) 2016-07-14 US disclosed
US-20100227076-A1 INK COMPOSITION AND INKJET RECORDING METHOD FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20100075061-A1 INK COMPOSITION, INKJET RECORDING METHOD AND METHOD FOR PRODUCING PRINTED FORMED ARTICLE FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20100055613-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2010-03-04 US disclosed
US-20080305292-A1 Antifouling material using hydroxyl group-containing acrylamide derivative and use thereof OKAZAKI KOUJU 2008-12-11 US disclosed
US-20080241739-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080241740-A1 Support with photosensitive layer; reduce contact angle of water drops FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080199804-A1 Including free radical binder polymer containing functional group having dipole moment of 3.8 debye; laser computer controlled direct plate making without alkali development; sensitivity, printing durability FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080194762-A1 Polyurethanes, acryl resins, and metal (cobalt, nickel, palladium, and/or ruthenium); engravable flexographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080090943-A1 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION, INC. 2008-04-17 US disclosed
US-20080090943-A1 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION, INC. 2008-04-17 US disclosed