Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021081 | 0.91 | TSHR (1.00) | TSHRTDP1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL22627334 | 0.90 | TSHR (0.86) | TSHRTDP1KCNA3 | |
| SCHEMBL15171908 | 0.89 | TSHR (0.84) | TSHRTDP1 | |
| SCHEMBL1753416 | 0.89 | TSHR (0.71) | TSHRTDP1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL16684434 | 0.89 | TSHR (0.84) | TSHRTDP1KCNA3 | |
| SCHEMBL10014286 | 0.88 | TSHR (0.64) | TSHRTDP1OPRM1OPRL1ALDH1A1 | |
| SCHEMBL22627154 | 0.87 | TSHR (0.82) | TSHRTDP1KCNA3 | |
| SCHEMBL10044269 | 0.86 | TSHR (0.84) | TSHRTDP1ALDH1A1 | |
| SCHEMBL12394889 | 0.86 | TSHR (0.84) | TSHRTDP1 | |
| SCHEMBL10203832 | 0.85 | TSHR (0.61) | TSHRTDP1OPRM1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170112607-A1 | MULTIPURPOSE IMPLANT WITH MODELED SURFACE STRUCTURE FOR SOFT TISSUE RECONSTRUCTION | IconLab USA, Inc. | 2017-04-27 | — | — | US | disclosed |
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2017-02-23 | — | — | US | disclosed |
| US-20160096292-A1 | Method of Manufacturing an Artificial Elastic Implant for Restorative an Reconstructive Surgery | ICONLAB, USA, INC. | 2016-04-07 | — | — | US | disclosed |
| US-20130183262-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | NAVY, SECRETARY OF THE UNITED STATES OF AMERICA | 2013-07-18 | — | — | US | disclosed |
| WO-2012027729-A1 | FLUORINATED ETHOXYLATED POLYURETHANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183262-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | SLC11A2, ARG1, NGLY1 | TSHR 3398/4885TDP1 3822/4885OPRM1 736/4885 |
| US-20170049109-A1 | ANTIMICROBIAL POLYMERIC COMPOSITIONS | SLC11A2, ARG1, NGLY1 | TSHR 3398/4885TDP1 3822/4885OPRM1 736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.