Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27925927 | 1.00 | MAPT (0.66) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL1959983 | 0.98 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL1959985 | 0.98 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL17679310 | 0.92 | MAPT (0.70) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL29131601 | 0.92 | MAPT (0.70) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL28309024 | 0.88 | MAPT (0.51) | MAPTALDH1A1HCAR2FAAHCYP4F2 | |
| SCHEMBL25404144 | 0.87 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 | |
| SCHEMBL873713 | 0.87 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 | |
| SCHEMBL6309026 | 0.87 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 | |
| SCHEMBL11795363 | 0.87 | MAPT (0.68) | MAPTALDH1A1HCAR2FAAHALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857010-A1 | DIHYDROOROTIC ACID DEHYDROGENASE INHIBITOR | NAI Inc. (JP) | 2015-04-08 | — | — | EP | disclosed |
| EP-1937619-B1 | NOVEL UNSATURATED FATTY HYDROXY ACID DERIVATIVES AND THE DERMOCOSMETOLOGIC USE THEREOF | PIERRE FABRE DERMO COSMÉTIQUE (FR) | 2014-10-08 | — | — | EP | disclosed |
| EP-2636663-A1 | NOVEL DIHYDROXYBENZENE DERIVATIVES AND ANTIPROTOZOAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | aRigen Pharmaceuticals, Inc. (JP) | 2013-09-11 | — | — | EP | disclosed |
| US-8158811-B2 | Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-04-17 | — | — | US | disclosed |
| US-8158811-B2 | Unsaturated fatty hydroxy acid derivatives and the dermocosmetologic use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2012-04-17 | — | — | US | disclosed |
| US-20090238784-A1 | Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2009-09-24 | — | — | US | disclosed |
| US-20090238784-A1 | Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2009-09-24 | — | — | US | disclosed |
| WO-2007045693-A1 | NOVEL UNSATURATED FATTY HYDROXY ACID DERIVATIVES AND THE DERMOCOSMETOLOGIC USE THEREOF | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2007-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238784-A1 | Novel Unsaturated Fatty Hydroxy Acid Derivatives and the Dermocosmetologic Use Thereof | ELOVL3, FFAR3, FASN | MAPT 4625/4885ALDH1A1 861/4885HCAR2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.