ELOVL3

Very long chain fatty acid elongase 3 · Q9HB03 · ELOVL3 on Sugi Atlas →

454 patent compounds predicted against ELOVL3, 383 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL486146 SCHEMBL486146 1.00 6/20
SCHEMBL486176 SCHEMBL486176 1.00 6/20
SCHEMBL486252 SCHEMBL486252 1.00 6/20
SCHEMBL486337 SCHEMBL486337 1.00 6/20
SCHEMBL486547 SCHEMBL486547 1.00 6/20
SCHEMBL486551 SCHEMBL486551 1.00 6/20
SCHEMBL486608 SCHEMBL486608 1.00 6/20
SCHEMBL486655 SCHEMBL486655 1.00 6/20
SCHEMBL486051 SCHEMBL486051 0.93 6/20
SCHEMBL486441 SCHEMBL486441 0.89 6/20
SCHEMBL486548 SCHEMBL486548 0.88 6/20
SCHEMBL486064 SCHEMBL486064 0.88 6/20
SCHEMBL486253 SCHEMBL486253 0.88 6/20
SCHEMBL486256 SCHEMBL486256 0.88 6/20
SCHEMBL486406 SCHEMBL486406 0.88 6/20
SCHEMBL486026 SCHEMBL486026 0.87 6/20
SCHEMBL486391 SCHEMBL486391 0.87 6/20
SCHEMBL486132 SCHEMBL486132 0.87 6/20
SCHEMBL486223 SCHEMBL486223 0.87 6/20
SCHEMBL486069 SCHEMBL486069 0.85 6/20

Clinical trials — most relevant to ELOVL3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Obesity and Asthma: Nutrigenetic Response to Omega-3 Fatty Acids PHASE2/PHASE3COMPLETED
A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders PHASE3UNKNOWN
Effect of Fish-oil on Non-alcoholic Steatohepatitis (NASH) PHASE2COMPLETED
Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver PHASE2COMPLETED
Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention PHASE2COMPLETED
Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy PHASE1COMPLETED
Omega-3 vs Very Low Calorie Diet for Liver Size Reduction nanUNKNOWN
The Effects of Milk Protein Versus Soy Protein on Essential Omega-3 Fatty Acid Metabolism nanACTIVE_NOT_RECRUITING
Canola Oil Multicentre Intervention Trial nanCOMPLETED
Acute Effects of Fats on Satiety and Energy Needs nanCOMPLETED
Fish Oil and Nonalcoholic Fatty Liver Disease (NAFLD) Study nanCOMPLETED
Genotype-related Effects of PUFA nanCOMPLETED
Sacha Inchi Oil Supplementation in 3Hs nanCOMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity nanCOMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish) nanUNKNOWN
Metabolic Actions of Omega-3 Fatty Acids nanCOMPLETED
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids. nanCOMPLETED
Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing nanCOMPLETED
Activity of Essential Fatty Acid Elongation/Desaturation Pathway During Early Life in Human Infants, In Vivo nanCOMPLETED
Genes, Omega-3 Fatty Acids and Cardiovascular Disease Risk Factors nanACTIVE_NOT_RECRUITING
Influence of the Background Diet on Metabolism of Land-based n-3 PUFA nanCOMPLETED
Krill Oil Supplementation: Effects on Breast Milk Composition nanCOMPLETED
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk nanCOMPLETED
Adjunct Use of Diode Laser Therapy and Omega 3 Gel in Local Drug Delivery Approach on The Treatment of Localized Aggressive Periodontitis nanCOMPLETED
Lipid Mediators in Multiple Sclerosis nanCOMPLETED
Exercise Intolerance Study in Long Chain Fatty Acid Oxidation Disorders nanRECRUITING
Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents nanACTIVE_NOT_RECRUITING
Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women nanCOMPLETED
Effect of n-3 Polyunsaturated Fatty Acids Supplementation on Human Milk Composition of Lactating Women nanCOMPLETED
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ELOVL3 binder may also engage these)

ProteinNameSimilarity
O35949 0.999 O35949 →
Q03574 0.996 Q03574 →
Q4D5J7 0.995 Q4D5J7 →
Q4DUK4 0.995 Q4DUK4 →
Q4DHY3 0.992 Q4DHY3 →
Q54TC9 0.992 Q54TC9 →
Q9JLJ5 0.991 Q9JLJ5 →
G5EEE5 0.990 G5EEE5 →
P49191 0.990 P49191 →
Q57UP6 0.988 Q57UP6 →
Q9XVQ9 0.988 Q9XVQ9 →
A0JNC4 0.988 A0JNC4 →
D4ADY9 0.987 D4ADY9 →
Q4QJ85 0.987 Q4QJ85 →
Q20303 0.986 Q20303 →
Q9VH58 0.986 Q9VH58 →
B4QVX4 0.986 B4QVX4 →
ELOVL1 Very long chain fatty acid elongase 1 0.985 landscape →
Q20300 0.984 Q20300 →
Q9D2Y9 0.984 Q9D2Y9 →
Q4D321 0.983 Q4D321 →
Q4DHY2 0.983 Q4DHY2 →
Q9VV87 0.983 Q9VV87 →
A1L3X0 0.982 A1L3X0 →
Q4DUK7 0.981 Q4DUK7 →
Q57UP7 0.979 Q57UP7 →
Q9NXB9 0.979 Q9NXB9 →
Q54CJ4 0.977 Q54CJ4 →
Q32NI8 0.977 Q32NI8 →
Q57UP8 0.977 Q57UP8 →